Synthesis and biological evaluation of pyridylpiperazine hybrid derivatives as urease inhibitors
Urease, a nickel-dependent enzyme found in various life forms, catalyzes urea breakdown, concluding nitrogen metabolism by generating ammonia and carbamate. This process causes a rise in pH, supports the survival of pathogens, and can lead to infections such as gastric disorders like ulcers and canc...
发表在: | FRONTIERS IN CHEMISTRY |
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Main Authors: | , , , , , |
格式: | 文件 |
语言: | English |
出版: |
FRONTIERS MEDIA SA
2024
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主题: | |
在线阅读: | https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001191125900001 |