Synthesis and biological evaluation of pyridylpiperazine hybrid derivatives as urease inhibitors
Urease, a nickel-dependent enzyme found in various life forms, catalyzes urea breakdown, concluding nitrogen metabolism by generating ammonia and carbamate. This process causes a rise in pH, supports the survival of pathogens, and can lead to infections such as gastric disorders like ulcers and canc...
出版年: | FRONTIERS IN CHEMISTRY |
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主要な著者: | , , , , , |
フォーマット: | 論文 |
言語: | English |
出版事項: |
FRONTIERS MEDIA SA
2024
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主題: | |
オンライン・アクセス: | https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001191125900001 |