Synthesis and biological evaluation of pyridylpiperazine hybrid derivatives as urease inhibitors

Urease, a nickel-dependent enzyme found in various life forms, catalyzes urea breakdown, concluding nitrogen metabolism by generating ammonia and carbamate. This process causes a rise in pH, supports the survival of pathogens, and can lead to infections such as gastric disorders like ulcers and canc...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:FRONTIERS IN CHEMISTRY
المؤلفون الرئيسيون: Akash, Muhammad; Zaib, Sumera; Ahmad, Matloob; Sultan, Sadia; Al-Hussain, Sami A.
التنسيق: مقال
اللغة:English
منشور في: FRONTIERS MEDIA SA 2024
الموضوعات:
الوصول للمادة أونلاين:https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001191125900001