Different concentrations of nivolumab reduce PD-1 expression but not tumour growth in an EMT6 mouse model

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Different concentrations of nivolumab reduce PD-1 expression but not tumour growth in an EMT6 mouse model

Introduction: The interaction between the T cell immune checkpoint proteins, the programmed death-1 (PD -1) receptor, and its ligand PD -L1 plays a crucial role in T cell suppression and the evasion of cancer cells from immune detection, thereby promoting tumour growth. Nivolumab, a PD -1 inhibitor,...

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Bibliographic Details
Published in:	BIOMEDICAL RESEARCH AND THERAPY
Main Authors:	Sham, Nur Fatihah Ronny; Hasbullah, Harissa Husainy; Hasani, Narimah Abdul Hamid; Hasan, Nurhaslina; Othman, Suraya; Osman, Nora Julianna; Karim, Muhammad Khalis Abdul; Fuad, Syed Baharom Syed Ahmad; Ibahim, Mohammad Johari
Format:	Article
Language:	English
Published:	BIOMEDPRESS 2024
Subjects:	Research & Experimental Medicine
Online Access:	https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001181825100001

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