YOLO and residual network for colorectal cancer cell detection and counting
The HT-29 cell line, derived from human colon cancer, is valuable for biological and cancer research applications. Early detection is crucial for improving the chances of survival, and researchers are introducing new techniques for accurate cancer diagnosis. This study introduces an efficient deep l...
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Language: | English |
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CELL PRESS
2024
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Online Access: | https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001169901400001 |
author |
Haq Inayatul; Mazhar Tehseen; Asif Rizwana Naz; Ghadi Yazeed Yasin; Ullah Najib; Khan Muhammad Amir; Al-Rasheed Amal |
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Haq Inayatul; Mazhar Tehseen; Asif Rizwana Naz; Ghadi Yazeed Yasin; Ullah Najib; Khan Muhammad Amir; Al-Rasheed Amal YOLO and residual network for colorectal cancer cell detection and counting Science & Technology - Other Topics |
author_facet |
Haq Inayatul; Mazhar Tehseen; Asif Rizwana Naz; Ghadi Yazeed Yasin; Ullah Najib; Khan Muhammad Amir; Al-Rasheed Amal |
author_sort |
Haq |
spelling |
Haq, Inayatul; Mazhar, Tehseen; Asif, Rizwana Naz; Ghadi, Yazeed Yasin; Ullah, Najib; Khan, Muhammad Amir; Al-Rasheed, Amal YOLO and residual network for colorectal cancer cell detection and counting HELIYON English Article The HT-29 cell line, derived from human colon cancer, is valuable for biological and cancer research applications. Early detection is crucial for improving the chances of survival, and researchers are introducing new techniques for accurate cancer diagnosis. This study introduces an efficient deep learning-based method for detecting and counting colorectal cancer cells (HT-29). The colorectal cancer cell line was procured from a company. Further, the cancer cells were cultured, and a transwell experiment was conducted in the lab to collect the dataset of colorectal cancer cell images via fluorescence microscopy. Of the 566 images, 80 % were allocated to the training set, and the remaining 20 % were assigned to the testing set. The HT-29 cell detection and counting in medical images is performed by integrating YOLOv2, ResNet-50, and ResNet-18 architectures. The accuracy achieved by ResNet-18 is 98.70 % and ResNet-50 is 96.66 %. The study achieves its primary objective by focusing on detecting and quantifying congested and overlapping colorectal cancer cells within the images. This innovative work constitutes a significant development in overlapping cancer cell detection and counting, paving the way for novel advancements and opening new avenues for research and clinical applications. Researchers can extend the study by exploring variations in ResNet and YOLO architectures to optimize object detection performance. Further investigation into real-time deployment strategies will enhance the practical applicability of these models. CELL PRESS 2405-8440 2024 10 2 10.1016/j.heliyon.2024.e24403 Science & Technology - Other Topics Green Published, gold WOS:001169901400001 https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001169901400001 |
title |
YOLO and residual network for colorectal cancer cell detection and counting |
title_short |
YOLO and residual network for colorectal cancer cell detection and counting |
title_full |
YOLO and residual network for colorectal cancer cell detection and counting |
title_fullStr |
YOLO and residual network for colorectal cancer cell detection and counting |
title_full_unstemmed |
YOLO and residual network for colorectal cancer cell detection and counting |
title_sort |
YOLO and residual network for colorectal cancer cell detection and counting |
container_title |
HELIYON |
language |
English |
format |
Article |
description |
The HT-29 cell line, derived from human colon cancer, is valuable for biological and cancer research applications. Early detection is crucial for improving the chances of survival, and researchers are introducing new techniques for accurate cancer diagnosis. This study introduces an efficient deep learning-based method for detecting and counting colorectal cancer cells (HT-29). The colorectal cancer cell line was procured from a company. Further, the cancer cells were cultured, and a transwell experiment was conducted in the lab to collect the dataset of colorectal cancer cell images via fluorescence microscopy. Of the 566 images, 80 % were allocated to the training set, and the remaining 20 % were assigned to the testing set. The HT-29 cell detection and counting in medical images is performed by integrating YOLOv2, ResNet-50, and ResNet-18 architectures. The accuracy achieved by ResNet-18 is 98.70 % and ResNet-50 is 96.66 %. The study achieves its primary objective by focusing on detecting and quantifying congested and overlapping colorectal cancer cells within the images. This innovative work constitutes a significant development in overlapping cancer cell detection and counting, paving the way for novel advancements and opening new avenues for research and clinical applications. Researchers can extend the study by exploring variations in ResNet and YOLO architectures to optimize object detection performance. Further investigation into real-time deployment strategies will enhance the practical applicability of these models. |
publisher |
CELL PRESS |
issn |
2405-8440 |
publishDate |
2024 |
container_volume |
10 |
container_issue |
2 |
doi_str_mv |
10.1016/j.heliyon.2024.e24403 |
topic |
Science & Technology - Other Topics |
topic_facet |
Science & Technology - Other Topics |
accesstype |
Green Published, gold |
id |
WOS:001169901400001 |
url |
https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001169901400001 |
record_format |
wos |
collection |
Web of Science (WoS) |
_version_ |
1809678796675088384 |