TRPM4 blocking antibody reduces neuronal excitotoxicity by specifically inhibiting glutamate-induced calcium influx under chronic hypoxia
Excitotoxicity arises from unusually excessive activation of excitatory amino acid receptors such as glutamate receptors. Following an energy crisis, excitotoxicity is a major cause for neuronal death in neurological disorders. Many glutamate antagonists have been examined for their efficacy in miti...
| Published in: | NEUROBIOLOGY OF DISEASE |
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| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
ACADEMIC PRESS INC ELSEVIER SCIENCE
2024
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| Subjects: | |
| Online Access: | https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001166358900001 |