Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study

Background Finding innovative methods to enhance Tuberculosis treatment adherence in Malaysia is imperative, given the rising trend of non-adhere TB patients. Direct Observed Therapy (DOTS) has been used to ensure Tuberculosis (TB) drug compliance worldwide. However, due to its inconvenience, digita...

Full description

Bibliographic Details
Published in:BMC PUBLIC HEALTH
Main Authors: Abas, Siti Aishah; Ismail, Nurhuda; Zakaria, Yuslina; Yasin, Siti Munira; Ibrahim, Khalid; Ismail, Ismassabah; Razali, Asmah; Sherzkawi, Mas Ahmad; Ahmad, Norliza
Format: Article
Language:English
Published: BMC 2024
Subjects:
Online Access:https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001155087900018
author Abas
Siti Aishah; Ismail
Nurhuda; Zakaria
Yuslina; Yasin
Siti Munira; Ibrahim
Khalid; Ismail
Ismassabah; Razali
Asmah; Sherzkawi
Mas Ahmad; Ahmad
Norliza
spellingShingle Abas
Siti Aishah; Ismail
Nurhuda; Zakaria
Yuslina; Yasin
Siti Munira; Ibrahim
Khalid; Ismail
Ismassabah; Razali
Asmah; Sherzkawi
Mas Ahmad; Ahmad
Norliza
Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study
Public, Environmental & Occupational Health
author_facet Abas
Siti Aishah; Ismail
Nurhuda; Zakaria
Yuslina; Yasin
Siti Munira; Ibrahim
Khalid; Ismail
Ismassabah; Razali
Asmah; Sherzkawi
Mas Ahmad; Ahmad
Norliza
author_sort Abas
spelling Abas, Siti Aishah; Ismail, Nurhuda; Zakaria, Yuslina; Yasin, Siti Munira; Ibrahim, Khalid; Ismail, Ismassabah; Razali, Asmah; Sherzkawi, Mas Ahmad; Ahmad, Norliza
Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study
BMC PUBLIC HEALTH
English
Article
Background Finding innovative methods to enhance Tuberculosis treatment adherence in Malaysia is imperative, given the rising trend of non-adhere TB patients. Direct Observed Therapy (DOTS) has been used to ensure Tuberculosis (TB) drug compliance worldwide. However, due to its inconvenience, digitalizing this system into a virtual monitoring system via a mobile app can help deliver a more efficient tuberculosis management system. A gamified video-observed therapy is developed that connects three users the patient, supervisor, and administrator, allowing drug monitoring and patient loss to follow up with the patient tracking system. Thus, the objective of this study is to determine the impact of Gamified Real-time Video Observed Therapy (GRVOTS) mobile apps on patient medication adherence rates and motivation. Methods 71 patients from 18 facilities participated in the 8-week single-arm intervention study. GRVOTS mobile apps were installed in their mobile apps, and patients were expected to fulfill tasks such as providing Video Direct Observe Therapy (VDOTS) daily as well as side effect reporting. At 3-time intervals of baseline,1-month, and 2-month intervals, the number of VDOT taken, the Malaysian Medication Adherence Assessment Tool (MyMAAT), and the Intrinsic Motivation Inventory (IMI) questionnaire were collected. One-sample t-test was conducted comparing the VDOT video adherence to the standard rate of 80%. RM ANOVA was used to analyze any significant differences in MyMAAT and IMI scores across three-time intervals. Results This study involved 71 numbers of patients from 18 healthcare facilities who showed a significantly higher treatment adherence score of 90.87% than a standard score of 80% with a mean difference of 10.87(95% CI: 7.29,14.46; p < 0.001). The participants' MyMAAT and IMI scores significantly increased over 3-time intervals with the IMI Interest domain showing the highest mean difference 19.76 (95% CI: 16.37, 21.152: p < 0.001). Conclusions By utilizing GRVOTS, a mobile application based on gamification and real-time features, we can enhance motivation and medication adherence among TB patients, while also addressing the limitations of physical DOTS. Trial registrationIRCT20230308057657N1, Registered on (15/03/23).
BMC

1471-2458
2024
24
1
10.1186/s12889-023-17561-z
Public, Environmental & Occupational Health
gold
WOS:001155087900018
https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001155087900018
title Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study
title_short Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study
title_full Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study
title_fullStr Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study
title_full_unstemmed Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study
title_sort Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study
container_title BMC PUBLIC HEALTH
language English
format Article
description Background Finding innovative methods to enhance Tuberculosis treatment adherence in Malaysia is imperative, given the rising trend of non-adhere TB patients. Direct Observed Therapy (DOTS) has been used to ensure Tuberculosis (TB) drug compliance worldwide. However, due to its inconvenience, digitalizing this system into a virtual monitoring system via a mobile app can help deliver a more efficient tuberculosis management system. A gamified video-observed therapy is developed that connects three users the patient, supervisor, and administrator, allowing drug monitoring and patient loss to follow up with the patient tracking system. Thus, the objective of this study is to determine the impact of Gamified Real-time Video Observed Therapy (GRVOTS) mobile apps on patient medication adherence rates and motivation. Methods 71 patients from 18 facilities participated in the 8-week single-arm intervention study. GRVOTS mobile apps were installed in their mobile apps, and patients were expected to fulfill tasks such as providing Video Direct Observe Therapy (VDOTS) daily as well as side effect reporting. At 3-time intervals of baseline,1-month, and 2-month intervals, the number of VDOT taken, the Malaysian Medication Adherence Assessment Tool (MyMAAT), and the Intrinsic Motivation Inventory (IMI) questionnaire were collected. One-sample t-test was conducted comparing the VDOT video adherence to the standard rate of 80%. RM ANOVA was used to analyze any significant differences in MyMAAT and IMI scores across three-time intervals. Results This study involved 71 numbers of patients from 18 healthcare facilities who showed a significantly higher treatment adherence score of 90.87% than a standard score of 80% with a mean difference of 10.87(95% CI: 7.29,14.46; p < 0.001). The participants' MyMAAT and IMI scores significantly increased over 3-time intervals with the IMI Interest domain showing the highest mean difference 19.76 (95% CI: 16.37, 21.152: p < 0.001). Conclusions By utilizing GRVOTS, a mobile application based on gamification and real-time features, we can enhance motivation and medication adherence among TB patients, while also addressing the limitations of physical DOTS. Trial registrationIRCT20230308057657N1, Registered on (15/03/23).
publisher BMC
issn
1471-2458
publishDate 2024
container_volume 24
container_issue 1
doi_str_mv 10.1186/s12889-023-17561-z
topic Public, Environmental & Occupational Health
topic_facet Public, Environmental & Occupational Health
accesstype gold
id WOS:001155087900018
url https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001155087900018
record_format wos
collection Web of Science (WoS)
_version_ 1809678633445359616