Molecular docking and dynamics simulations revealed the potential inhibitory activity of honey-iQfood ingredients against GSK-3β and CDK5 protein targets for brain health

QR Code

Molecular docking and dynamics simulations revealed the potential inhibitory activity of honey-iQfood ingredients against GSK-3β and CDK5 protein targets for brain health

Honey-iQfood is an herbal supplement made of a mixture of polyherbal extracts and wild honey. The mixture is traditionally claimed to improve various conditions related to brain cells and functions including dementia and Alzheimer's disease. Glycogen synthase kinase-3 beta (GSK-3 beta) and cycl...

Full description

Bibliographic Details
Published in:	JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
Main Authors:	Zakaria, Nor Hafizah; Mohamed Tap, Fatahiya; Aljohani, Ghadah Faraj; Abdul Majid, Fadzilah Adibah
Format:	Article; Early Access
Language:	English
Published:	TAYLOR & FRANCIS INC 2023
Subjects:	Biochemistry & Molecular Biology; Biophysics
Online Access:	https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001137873000001

Similar Items

Molecular docking and dynamics simulations revealed the potential inhibitory activity of honey-iQfood ingredients against GSK-3β and CDK5 protein targets for brain health
by: Zakaria N.H.; Mohamed Tap F.; Aljohani G.F.; Abdul Majid F.A.
Published: (2023)

Mechanical properties of engineered cementitious composites using local ingredients
by: Wee L.S.; Lian O.C.; Zain M.R.M.
Published: (2019)

Pitaya powder potential as antioxidant functional ingredient in food products
by: Chik C.T.; Bachok S.; Baba N.; Abdullah A.; Wan Mustapha W.A.; Abdullah N.
Published: (2012)

Optimising the Nutritional Value of Kombucha Using Fruit Peels as Functional Ingredients
by: Fisol A.H.; Aziman N.
Published: (2024)

Stress-relieving properties of a polyherbal blend with Syzygium aromaticum L. and Coffea canephora Pierre ex A. Froehner: A review and bibliometric analysis
by: Zakaria, et al.
Published: (2024)

Comparative studies on the release behaviours of gallic acid and eurycomanone as active ingredients in herbal supplement
by: Noorazwani Z.; Nazurah M.A.; Arief M.A.M.E.; Khetiswari G.; Norulfairuz A.Z.D.
Published: (2022)

Safety and health risk assessment methodology of dermal and inhalation exposure to formulated products ingredients
by: Raslan R.; Hassim M.H.; Chemmangattuvalappil N.G.; Ng D.K.S.; Ten J.Y.
Published: (2020)

Physicochemical and biocompatibility characterisation of a 3D lyophilised platelet-rich fibrin scaffold for cleft lip and palate repair
by: Ngah, et al.
Published: (2024)

Dexibuprofen loaded into nanoemulsion based gel for topical application - In vitro characterization and in vivo anti-inflammatory evaluation
by: Munir, et al.
Published: (2025)

In vitro antioxidant and in silico enzyme inhibition studies of Carissa carandas Linn.: potential ingredient for nutraceutical development
by: Zubair M.; Tousif M.I.; Riaz N.; Saleem M.; Nazir M.; Tauseef S.; Hassan A.; Shah S.A.A.; Zengin G.; Hashem A.; Kumar A.; Abd_Allah E.F.
Published: (2024)

Optical Microfiber Sensing of Adulterated Honey
by: Irawati N.; Isa N.M.; Mohamed A.F.; Rahman H.A.; Harun S.W.; Ahmad H.
Published: (2017)

Revealing the unseen: a bibliometric analysis of workplace safety
by: Abdullah, et al.
Published: (2023)

Revealing the non-Muslim Kopitiams and the awarded Halal Signage
by: Embong A.M.; Yaacob R.A.I.R.; Sabian N.A.A.; Noor A.B.M.; Mohamad R.; Lahmuddin A.H.
Published: (2018)

Silica microfiber sensor for the detection of honey adulteration
by: Isa N.M.; Irawati N.; Rosol A.H.A.; Rahman H.A.; Ismail W.I.W.; Yusoff M.H.M.; Naim N.F.
Published: (2017)

Physicochemical analysis and sugar profiling of Acacia honey
by: Mohamed A.S.; Abdah M.A.; Ramasamy K.; Hasan M.H.; Aida Hamimi I.; Zolkapli E.
Published: (2018)

Neuroprotective Potentials of Honey for Cerebral Small Vessel Disease
by: Nassir C.M.N.C.M.; Hamid H.A.; Hambali A.; Manan N.A.; Mehat M.Z.; Ismail N.I.; Mustapha M.
Published: (2022)

Process standardization and characterization of Mies: Ethiopian honey wine
by: Gebremichael W.M.; Abay K.H.; Sbhatu D.B.; Berhe G.G.; Gebreyohannes G.
Published: (2024)

Centella asiatica protects D-galactose/AlCl3 mediated alzheimer’s disease-like rats via PP2A/GSK-3β signaling pathway in their hippocampus
by: Chiroma S.M.; Baharuldin M.T.H.; Taib C.N.M.; Amom Z.; Jagadeesan S.; Adenan M.I.; Mahdi O.; Moklas M.A.M.
Published: (2019)

Dielectric properties assessment of honey by using nondestructive dielectric spectroscopy
by: Bakar A.A.; bin Rodzali M.A.N.; Radzali R.; Idris A.; Razali A.R.
Published: (2022)

Learning Analytics to Reveal Links Between Learning Design and Self-Regulated Learning
by: Fan Y.; Matcha W.; Uzir N.A.; Wang Q.; Gašević D.
Published: (2021)

REVEALING THE ROLES OF MUSIC EDUCATION IN STEAM CURRICULUM FOR CULTURAL EXPLORATION AND HISTORICAL RESONANCE
by: Sile H.; Ismail M.J.; Bing Z.
Published: (2024)

Anti-inflammatory effects of manuka honey on salivary cytokines (clinical study)
by: Al-Kubaisi M.W.; Al-Ghurabi B.H.; Alkubaisy W.; Abdullah N.N.
Published: (2023)

Detection of honey adulteration by addition of glucose via a microfiber coupler
by: Rosol A.H.A.; Isa N.M.; Irawati N.; Rahman H.A.; Harun S.W.
Published: (2017)

Modulation of vulvovaginal atrophy (VVA) by Gelam honey in bilateral oophorectomized rats
by: Ismail N.H.; Ibrahim S.F.; Mokhtar M.H.; Yahaya A.; Zulkefli A.F.; Ankasha S.J.; Osman K.
Published: (2023)

An Optimized Honey Dehydration System with Drying Air Temperature and Relative Humidity Control
by: Abid A.; Yunus M.A.M.; Sahlan S.; Ramli M.M.; Amin M.R.A.; Lotpi Z.F.M.; Anuar N.H.K.
Published: (2019)

The role of Gelam honey in accelerating reepithelialization of ex vivo corneal abrasion model
by: Azmi M.F.; Abd Ghafar N.; Che Hamzah J.; Chua K.H.; Ng S.L.
Published: (2021)

Effects of pure and fake honey on glucose and lipid profile in vitro and in vivo study
by: Zulkifli M.F.; Samat S.; Azam N.S.M.; Enchang F.K.; Razak A.A.; Hussein F.N.; Ismail W.I.W.
Published: (2020)

Revealing the Effects of Various Acid Dopants on the Electrical Conductivity and Electrochemical Activity of Conductive Polyaniline Fabrics
by: Aizamddin M.F.; Saaid F.I.; Megat Zakaria P.N.; Mahat M.M.
Published: (2023)

Coffee consumption revealed sex differences in host endogenous metabolism and gut microbiota in healthy adults
by: Chong C.W.; Wong L.C.; Teh C.S.J.; Ismail N.H.; Chan P.Q.; Lim C.S.; Yap S.C.; Yap I.K.S.
Published: (2020)

Identification of cancer inhibitors from Hystrix brachyura bezoar extracts using LC-MS multivariate data analysis and in silico evaluation on Bcl-2, cyclin B/CDK1, VEGF and NM23-H1; [Identificación de inhibidores de cáncer a partir de extractos de bezoar de Hystrix branchyura usando análisis multivariado LC-MS y evaluación in silico en Bcl-2, cyclin B/CDK1, VEGF, y NM23-H1]
by: Khan A.A.Y.F.; Ahmed Q.U.; Khatib A.; Ibrahim Z.; Nipun T.S.; Natto H.A.; Saiman M.Z.; Zakaria Z.A.; Wahab R.A.
Published: (2024)

Effects of Gelam and Acacia honey acute administration on some biochemical parameters of Sprague Dawley rats
by: Samat S.; Nor N.A.M.; Nor Hussein F.; Ismail W.I.W.
Published: (2014)

A review on internet of things-based stingless bee's honey production with image detection framework
by: Rohafauzi S.; Kassim M.; Ja’afar H.; Rustam I.; Miskon M.T.
Published: (2024)

Gelam honey attenuates ovalbumin-induced airway inflammation in a mice model of allergic asthma
by: Shamshuddin N.S.S.; Mohd Zohdi R.
Published: (2018)

The Trend in Established Analytical Techniques in the Investigation of Physicochemical Properties and Various Constituents of Honey: a Review
by: Manickavasagam G.; Saaid M.; Osman R.
Published: (2022)

Zinc: Indications in brain disorders
by: Prakash A.; Bharti K.; Majeed A.B.A.
Published: (2015)

Revealing the unseen: a bibliometric analysis of workplace safety; [Odhalení neviditelného: bibliometrická analýza bezpečnosti na pracovišti]
by: Abdullah K.H.; Roslan M.F.; Ishak N.S.; Ishak N.S.; Yahya M.A.; Hadi H.R.A.; Rosaai M.S.N.M.
Published: (2023)

Revealing the improved sensitivity of PEDOT:PSS/PVA thin films through secondary doping and their strain sensors application
by: Ahmad Ruzaidi D.A.; Maurya M.R.; Yempally S.; Abdul Gafoor S.; Geetha M.; Che Roslan N.; Cabibihan J.-J.; Kumar Sadasivuni K.; Mahat M.M.
Published: (2023)

Automated segmentation and detection of T1-weighted magnetic resonance imaging brain images of glioma brain tumor
by: Zaihani N.H.I.M.; Roslan R.; Ibrahim Z.; Samah K.A.F.A.
Published: (2020)

Gelam (Melaleuca sp.) honey demonstrates antiproliferative effect on colon cancer cell lines (HCT116)
by: Fadhli M.R.M.N.; Noorfathiah I.; Hana M.A.N.F.; Ashraf M.S.M.; Zolkapli E.; Mizaton H.H.; Iryani W.I.W.
Published: (2012)

A honey badger algorithm for optimal sizing of an AC coupled hybrid stand-alone photovoltaic system
by: Kamarzaman N.A.; Sulaiman S.I.; Yassin A.I.M.; Ibrahim I.R.; Zainuddin H.
Published: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7enp8l0h2uuffuc5eigg2plpel