Unexplained subfertility: active or conservative management?
Objectives Unexplained subfertility (UEI) describes a couple whose standard subfertility workout consider acceptable but unable to conceived.Methods This retrospective study was conducted in the Advanced Reproductive Centre, UKM Hospital, Kuala Lumpur, from January 2016 to December 2019. The data of...
Published in: | HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION |
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Main Authors: | , , , , , |
Format: | Article; Early Access |
Language: | English |
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WALTER DE GRUYTER GMBH
2024
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Online Access: | https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001130638000001 |
author |
Ahmad Siti Maisarah; Jin Norazilah Mat; Ahmad Mohd Faizal; Karim Abdul Kadir Abdul; Abu Muhammad Azrai |
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Ahmad Siti Maisarah; Jin Norazilah Mat; Ahmad Mohd Faizal; Karim Abdul Kadir Abdul; Abu Muhammad Azrai Unexplained subfertility: active or conservative management? Biochemistry & Molecular Biology |
author_facet |
Ahmad Siti Maisarah; Jin Norazilah Mat; Ahmad Mohd Faizal; Karim Abdul Kadir Abdul; Abu Muhammad Azrai |
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Ahmad |
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Ahmad, Siti Maisarah; Jin, Norazilah Mat; Ahmad, Mohd Faizal; Karim, Abdul Kadir Abdul; Abu Muhammad, Azrai Unexplained subfertility: active or conservative management? HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION English Article; Early Access Objectives Unexplained subfertility (UEI) describes a couple whose standard subfertility workout consider acceptable but unable to conceived.Methods This retrospective study was conducted in the Advanced Reproductive Centre, UKM Hospital, Kuala Lumpur, from January 2016 to December 2019. The data of 268 UEI couples were obtained from the clinical database. Women aged 21-45 years old was included and further divided into four groups according to the female partner's age and subfertility duration: group A (age <35 years and subfertility <2 years), group B (age <35 years and subfertility >2 years), group C (age >35 years and subfertility <2 years), and group D (age >35 years and subfertility <2 years). All statistical analyses were performed using SPSS 22.0 for Windows.Results A total of 255 cases were included in this study. The mean age of the women was 32.9 +/- 4.04 years, and the mean subfertility duration was 5.04 +/- 2.9 years. A total of 51 (20 %) cases underwent timed sexual intercourse, 147 (57.6 %) cases had intrauterine insemination (IUI), whereas 57 (22.4 %) cases opted for in vitro fertilization (IVF). A total of 204 cases underwent active management (IUI/IVF), which showed a significant difference (p<0.05). Out of eight clinical pregnancies, half of them were from group B.Conclusions Active management in younger women with a shorter subfertility duration revealed a better pregnancy outcome. Otherwise, individualized treatment should be considered in selecting a suitable treatment plan. WALTER DE GRUYTER GMBH 1868-1883 1868-1891 2024 44 4 10.1515/hmbci-2022-0087 Biochemistry & Molecular Biology WOS:001130638000001 https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001130638000001 |
title |
Unexplained subfertility: active or conservative management? |
title_short |
Unexplained subfertility: active or conservative management? |
title_full |
Unexplained subfertility: active or conservative management? |
title_fullStr |
Unexplained subfertility: active or conservative management? |
title_full_unstemmed |
Unexplained subfertility: active or conservative management? |
title_sort |
Unexplained subfertility: active or conservative management? |
container_title |
HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION |
language |
English |
format |
Article; Early Access |
description |
Objectives Unexplained subfertility (UEI) describes a couple whose standard subfertility workout consider acceptable but unable to conceived.Methods This retrospective study was conducted in the Advanced Reproductive Centre, UKM Hospital, Kuala Lumpur, from January 2016 to December 2019. The data of 268 UEI couples were obtained from the clinical database. Women aged 21-45 years old was included and further divided into four groups according to the female partner's age and subfertility duration: group A (age <35 years and subfertility <2 years), group B (age <35 years and subfertility >2 years), group C (age >35 years and subfertility <2 years), and group D (age >35 years and subfertility <2 years). All statistical analyses were performed using SPSS 22.0 for Windows.Results A total of 255 cases were included in this study. The mean age of the women was 32.9 +/- 4.04 years, and the mean subfertility duration was 5.04 +/- 2.9 years. A total of 51 (20 %) cases underwent timed sexual intercourse, 147 (57.6 %) cases had intrauterine insemination (IUI), whereas 57 (22.4 %) cases opted for in vitro fertilization (IVF). A total of 204 cases underwent active management (IUI/IVF), which showed a significant difference (p<0.05). Out of eight clinical pregnancies, half of them were from group B.Conclusions Active management in younger women with a shorter subfertility duration revealed a better pregnancy outcome. Otherwise, individualized treatment should be considered in selecting a suitable treatment plan. |
publisher |
WALTER DE GRUYTER GMBH |
issn |
1868-1883 1868-1891 |
publishDate |
2024 |
container_volume |
44 |
container_issue |
4 |
doi_str_mv |
10.1515/hmbci-2022-0087 |
topic |
Biochemistry & Molecular Biology |
topic_facet |
Biochemistry & Molecular Biology |
accesstype |
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id |
WOS:001130638000001 |
url |
https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001130638000001 |
record_format |
wos |
collection |
Web of Science (WoS) |
_version_ |
1809678576849518592 |