Inhibition of prostaglandin E2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation

The discovery of potent inhibitors of prostaglandin E2 (PGE 2) synthesis in recent years has been proven to be an important game changer in pharmaceutical industry. It is known that excessive production of PGE2 triggers a vast array of biological signals and physiological events that contributes to...

詳細記述

書誌詳細
出版年:Bioorganic and Medicinal Chemistry Letters
第一著者: 2-s2.0-84905899348
フォーマット: 論文
言語:English
出版事項: Elsevier Ltd 2014
オンライン・アクセス:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905899348&doi=10.1016%2fj.bmcl.2014.06.061&partnerID=40&md5=621287f1c20ac7c89bdc516f2f4e8182