Synthesis, biological evaluation, molecular docking and dynamic simulation of novel benzofuran derivatives as potential agents against Alzheimer's disease

We have synthesized novel benzofuran derivatives (1–20), characterized through different spectroscopic techniques such as 1HNMR, 13CNMR, HREI-MS and screened against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes. All derivatives showed inhibitory activities having IC50 values...

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发表在:Journal of Molecular Structure
主要作者: 2-s2.0-85206074124
格式: 文件
语言:English
出版: Elsevier B.V. 2025
在线阅读:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85206074124&doi=10.1016%2fj.molstruc.2024.140279&partnerID=40&md5=e40ae289255301808cdeec9a7a82529e