Synthesis, biological evaluation, molecular docking and dynamic simulation of novel benzofuran derivatives as potential agents against Alzheimer's disease
We have synthesized novel benzofuran derivatives (1–20), characterized through different spectroscopic techniques such as 1HNMR, 13CNMR, HREI-MS and screened against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes. All derivatives showed inhibitory activities having IC50 values...
发表在: | Journal of Molecular Structure |
---|---|
主要作者: | |
格式: | 文件 |
语言: | English |
出版: |
Elsevier B.V.
2025
|
在线阅读: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85206074124&doi=10.1016%2fj.molstruc.2024.140279&partnerID=40&md5=e40ae289255301808cdeec9a7a82529e |