The state of starch/hydroxyapatite composite scaffold in bone tissue engineering with consideration for dielectric measurement as an alternative characterization technique

Hydroxyapatite (HA) has been widely used as a scaffold in tissue engineering. HA possesses high mechanical stress and exhibits particularly excellent biocompatibility owing to its similarity to natural bone. Nonetheless, this ceramic scaffold has limited applications due to its apparent brittleness....

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发表在:Materials
主要作者: 2-s2.0-85104725074
格式: Review
语言:English
出版: MDPI AG 2021
在线阅读:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104725074&doi=10.3390%2fma14081960&partnerID=40&md5=35b5ed6161192b3667447a3038d4145a
id Mohd Roslan M.R.; Mohd Kamal N.L.; Abdul Khalid M.F.; Mohd Nasir N.F.; Cheng E.M.; Beh C.Y.; Tan J.S.; Mohamed M.S.
spelling Mohd Roslan M.R.; Mohd Kamal N.L.; Abdul Khalid M.F.; Mohd Nasir N.F.; Cheng E.M.; Beh C.Y.; Tan J.S.; Mohamed M.S.
2-s2.0-85104725074
The state of starch/hydroxyapatite composite scaffold in bone tissue engineering with consideration for dielectric measurement as an alternative characterization technique
2021
Materials
14
8
10.3390/ma14081960
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104725074&doi=10.3390%2fma14081960&partnerID=40&md5=35b5ed6161192b3667447a3038d4145a
Hydroxyapatite (HA) has been widely used as a scaffold in tissue engineering. HA possesses high mechanical stress and exhibits particularly excellent biocompatibility owing to its similarity to natural bone. Nonetheless, this ceramic scaffold has limited applications due to its apparent brittleness. Therefore, this had presented some difficulties when shaping implants out of HA and for sustaining a high mechanical load. Fortunately, these drawbacks can be improved by combining HA with other biomaterials. Starch was heavily considered for biomedical device applications in favor of its low cost, wide availability, and biocompatibility properties that complement HA. This review provides an insight into starch/HA composites used in the fabrication of bone tissue scaffolds and numerous factors that influence the scaffold properties. Moreover, an alternative characterization of scaffolds via dielectric and free space measurement as a potential contactless and nondestructive measurement method is also highlighted. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
MDPI AG
19961944
English
Review
All Open Access; Gold Open Access; Green Open Access
author 2-s2.0-85104725074
spellingShingle 2-s2.0-85104725074
The state of starch/hydroxyapatite composite scaffold in bone tissue engineering with consideration for dielectric measurement as an alternative characterization technique
author_facet 2-s2.0-85104725074
author_sort 2-s2.0-85104725074
title The state of starch/hydroxyapatite composite scaffold in bone tissue engineering with consideration for dielectric measurement as an alternative characterization technique
title_short The state of starch/hydroxyapatite composite scaffold in bone tissue engineering with consideration for dielectric measurement as an alternative characterization technique
title_full The state of starch/hydroxyapatite composite scaffold in bone tissue engineering with consideration for dielectric measurement as an alternative characterization technique
title_fullStr The state of starch/hydroxyapatite composite scaffold in bone tissue engineering with consideration for dielectric measurement as an alternative characterization technique
title_full_unstemmed The state of starch/hydroxyapatite composite scaffold in bone tissue engineering with consideration for dielectric measurement as an alternative characterization technique
title_sort The state of starch/hydroxyapatite composite scaffold in bone tissue engineering with consideration for dielectric measurement as an alternative characterization technique
publishDate 2021
container_title Materials
container_volume 14
container_issue 8
doi_str_mv 10.3390/ma14081960
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104725074&doi=10.3390%2fma14081960&partnerID=40&md5=35b5ed6161192b3667447a3038d4145a
description Hydroxyapatite (HA) has been widely used as a scaffold in tissue engineering. HA possesses high mechanical stress and exhibits particularly excellent biocompatibility owing to its similarity to natural bone. Nonetheless, this ceramic scaffold has limited applications due to its apparent brittleness. Therefore, this had presented some difficulties when shaping implants out of HA and for sustaining a high mechanical load. Fortunately, these drawbacks can be improved by combining HA with other biomaterials. Starch was heavily considered for biomedical device applications in favor of its low cost, wide availability, and biocompatibility properties that complement HA. This review provides an insight into starch/HA composites used in the fabrication of bone tissue scaffolds and numerous factors that influence the scaffold properties. Moreover, an alternative characterization of scaffolds via dielectric and free space measurement as a potential contactless and nondestructive measurement method is also highlighted. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
publisher MDPI AG
issn 19961944
language English
format Review
accesstype All Open Access; Gold Open Access; Green Open Access
record_format scopus
collection Scopus
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