Hydrophilic natural deep eutectic solvent: A review on physicochemical properties and extractability of bioactive compounds

The principle of green chemistry is crucial in the industrial processing of natural products. In particular, the extraction process of bioactive compounds from plant sources which involve food, nutraceutical, pharmaceutical, and cosmetic industries demand the use of green solvents. This is important...

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书目详细资料
发表在:Journal of Molecular Liquids
主要作者: 2-s2.0-85111472124
格式: Review
语言:English
出版: Elsevier B.V. 2021
在线阅读:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111472124&doi=10.1016%2fj.molliq.2021.116923&partnerID=40&md5=190e6bc67322b52f642f1f306485207c
实物特征
总结:The principle of green chemistry is crucial in the industrial processing of natural products. In particular, the extraction process of bioactive compounds from plant sources which involve food, nutraceutical, pharmaceutical, and cosmetic industries demand the use of green solvents. This is important to produce a value-added product that is safe for human consumption and the environment. Over the last few years, attention has been drawn towards the utilization of natural deep eutectic solvents (NADES) as the novel solvents in isolating bioactive compounds from natural sources. Its vast potential to replace conventional organic solvents and ionic liquids (IL) is realized due to their outstanding features which greatly comply with the green chemistry aspects. Since then, researchers are exploring endless opportunities for NADES, particularly the hydrophilic NADES to be used as an extraction media. This paper presents a review of the physicochemical properties of hydrophilic NADES. In view of the fact that these properties are responsible for NADES behaviour and its functionality, a comprehensive discussion on each property is presented. A detailed assessment of its properties provides a fundamental understanding associated with their molecular interactions and responses to the surrounding conditions. In addition, the solubilizing capacity of NADES towards bioactive compounds is also reviewed. © 2021 Elsevier B.V.
ISSN:1677322
DOI:10.1016/j.molliq.2021.116923