Benzoxazole based thiazole hybrid analogs: Synthesis, in vitro cholinesterase inhibition, and molecular docking studies
Acetylcholinesterase and butyrylcholinesterase enzymes are therapeutic target for Alzheimer disease and their inhibitors play a vital role for the treatment of this disease. A new series of benzoxazole based 1,3-thiazole hybrid scaffolds (1–20) were synthesized and assessed for acetylcholinesterase...
發表在: | Computational Toxicology |
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主要作者: | |
格式: | Article |
語言: | English |
出版: |
Elsevier B.V.
2023
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在線閱讀: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85145589794&doi=10.1016%2fj.comtox.2022.100253&partnerID=40&md5=5178a43a1fd89db398ecfc193cf9a56b |