Synthesis, kinetics, binding conformations and structure-activity relationship of potent tyrosinase inhibitors: Aralkylated 2-aminothiazole-ethyltriazole hybrids
Considering the diversified pharmacological importance of thiazole and triazole heterocyclic moieties, a unique series of S-aralkylated bi-heterocyclic hybrids, 7a-l, was synthesized in a convergent manner. The structures of newly synthesized compounds were characterized by 1 H-NMR,13C-NMR, IR, and...