Syntheses, in vitro evaluation and molecular docking studies of 5-bromo-2-aryl benzimidazoles as α-glucosidase inhibitors

Based on the previous reports on α-glucosidase inhibitory activity of benzimidazole class, we intend to evaluate further this class as potential inhibitors of α-glucosidase enzyme. Thus, in the current study synthesis of 5-bromo-2-aryl benzimidazole derivatives 1–25 was carried out. All the syntheti...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Medicinal Chemistry Research
المؤلف الرئيسي: 2-s2.0-84979210899
التنسيق: مقال
اللغة:English
منشور في: Birkhauser Boston 2016
الوصول للمادة أونلاين:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84979210899&doi=10.1007%2fs00044-016-1614-y&partnerID=40&md5=783f7712e81dcb8af6637a6d3aa7ba17