Trabecular meshwork ECM remodeling in glaucoma: could RAS be a target?
Introduction: Disturbances of extracellular matrix (ECM) homeostasis in trabecular meshwork (TM) cause increased aqueous outflow resistance leading to elevated intraocular pressure (IOP) in glaucomatous eyes. Therefore, restoration of ECM homeostasis is a rational approach to prevent disease progres...
Published in: | Expert Opinion on Therapeutic Targets |
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Main Author: | |
Format: | Review |
Language: | English |
Published: |
Taylor and Francis Ltd
2018
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049096441&doi=10.1080%2f14728222.2018.1486822&partnerID=40&md5=64f55f1df48cbd095a93ff671a3e32f2 |