Synthesis and biological evaluation of novel coumarin derivatives bearing sulfonamide moiety as potent α-glucosidase inhibitors
Acarbose, miglitol and voglibose are α-glucosidase enzyme inhibitors that are clinically used to treat type-II diabetes mellitus. However, they are also associated with several adverse side effects. In this study, a series of sulfonamide-substituted coumarin was synthesised in a three-step reaction...
Published in: | Journal of the Iranian Chemical Society |
---|---|
Main Author: | |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media Deutschland GmbH
2024
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85212866917&doi=10.1007%2fs13738-024-03143-2&partnerID=40&md5=83dfeff9edd9acadcfed5f1428722a6f |