α7-Nicotinic Acetylcholine Receptor Activation Modulates BV2 Microglial Plasticity via miR-21/TNF-α/NFκB in Oxygen–Glucose Deprivation/Reoxygenation

Elevated inflammatory reactions are a significant component in cerebral ischemia–reperfusion injury (CIRI). Activation of α7-Nicotinic Acetylcholine Receptor (α7nAChR) reduces stroke-induced inflammation in rats, but the anti-inflammatory pathway in microglia under CIRI condition remains unclear. Th...

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Bibliographic Details
Published in:Journal of Molecular Neuroscience
Main Author: Hasan M.Y.; Roslan A.H.M.; Azmi N.; Ibrahim N.M.; Arulsamy A.; Lee V.L.L.; Siran R.; Vidyadaran S.; Chua E.W.; Mahadi M.K.
Format: Article
Language:English
Published: Springer 2025
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85212794683&doi=10.1007%2fs12031-024-02300-9&partnerID=40&md5=bb2cee4db04d6058638dbaed22a96380

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