The Role of MicroRNAs in Chronic Myeloid Leukemia (CML) Treatment, Biomarkers, and Resistance to Tyrosine Kinase Inhibitor: A Bioinformatics-Based Analysis

Chronic myeloid leukemia (CML) is a myeloproliferative disorder caused by the reciprocal translocation of the BCR-ABL1 oncogene, which activates tyrosine kinase resulting in uncontrolled cell proliferation and apoptosis suppression. Although Imatinib (IM) is an effective treatment, IM resistance rem...

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Bibliographic Details
Published in:Journal of Tropical Life Science
Main Author: Mohamad S.F.S.; Ramlee R.A.; Elias M.H.
Format: Article
Language:English
Published: Brawijaya University 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85212240293&doi=10.11594%2fjtls.14.03.18&partnerID=40&md5=213b71b6ae9637915dcdfc0c2fe20c3e