Identification of new structure of indol-3-acetyl-arylsulfonohydrazide as potent α-glucosidase and α-amylase inhibitors and molecular docking
Herein this work, indole analogs (1–16) were synthesized by treating 2-(1H-indol-3-yl)acetohydrazide with various aryl sulfonyl chloride in pyridine as solvent and screened for α-amylase and α-glucosidase inhibitory activity under positive control of standard drug acarbose (IC50 = 12.80 ± 0.10 μM /1...
| Published in: | Journal of Molecular Structure |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier B.V.
2025
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85209591318&doi=10.1016%2fj.molstruc.2024.140719&partnerID=40&md5=013b2862aab435f98890306f743723cf |