Real-world analysis of safety, tolerability, and adherence to nirmatrelvir-ritonavir (paxlovid) in primary care COVID-19 outpatients

QR Code

Real-world analysis of safety, tolerability, and adherence to nirmatrelvir-ritonavir (paxlovid) in primary care COVID-19 outpatients

This retrospective cross-sectional study aims to evaluate the safety, tolerability, and adherence of patients prescribed Nirmatrelvir-ritonavir (Paxlovid) in outpatient settings, focusing on its use in managing category 2 COVID-19 patients across three primary healthcare clinics in Selangor, Malaysi...

Full description

Bibliographic Details
Published in:	Scientific Reports
Main Author:	Zaharuddin Z.; Md Hussin N.S.; Karuppannan M.
Format:	Article
Language:	English
Published:	Nature Research 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207226035&doi=10.1038%2fs41598-024-75192-9&partnerID=40&md5=a01ba6d65dc6484a3d30ff86ac06725c

Similar Items

Real-world analysis of safety, tolerability, and adherence to nirmatrelvir-ritonavir (paxlovid) in primary care COVID-19 outpatients
by: Zaharuddin, et al.
Published: (2024)

Antidepressant adherence among outpatients with major depressive disorder
by: Yassen A.O.; Mahmud N.M.; Bilal A.D.; Wahab M.S.A.
Published: (2024)

Guidelines adherence and hypertension control in an outpatient cardiology clinic in Malaysia
by: Ahmad N.; Hassan Y.; Tangiisuran B.; Meng O.L.; Aziz N.A.; Khan A.H.
Published: (2012)

Evaluation of Geriatric Medication Adherence using the General Medication Adherence Scale in a Primary Care Setting
by: Choudhury P.; Gnanasan S.; Ghadzi S.M.S.; Poddar S.
Published: (2023)

Predicting treatment adherence and outcome to outpatient multimodal rehabilitation in chronic low back pain
by: Dhondt E.; Van Oosterwijck J.; Cagnie B.; Adnan R.; Schouppe S.; Van Akeleyen J.; Logghe T.; Danneels L.
Published: (2020)

Real-world evaluation of care for type 2 diabetes in Malaysia: A cross-sectional analysis of the treatment adherence to guideline evaluation in type 2 diabetes (TARGET-T2D) study
by: Lim L.-L.; Hussein Z.; Noor N.M.; Abd Raof A.S.; Mustafa N.; Long Bidin M.B.; Ghani R.A.; Samsuddin S.; Yong S.-L.; Foo S.-H.; Raghuram K.; Suwannasri P.; Mohamad W.W.B.; Chiew T.-K.; Chan S.-P.
Published: (2024)

Real-world evaluation of care for type 2 diabetes in Malaysia: A cross-sectional analysis of the treatment adherence to guideline evaluation in type 2 diabetes (TARGET-T2D) study
by: Lim, et al.
Published: (2024)

Factors associated with inappropriate attitude towards antibiotic usage among outpatients of a public primary care specialist clinic: A cross sectional study
by: Zubaidi Z.S.A.; Malek K.A.; Ismail Z.
Published: (2021)

Feasibility, safety and clinical efficiency of optometric service pathways at primary and tertiary care level in ampang, malaysia: A pilot study
by: Hussin D.A.; Hendicott P.; Carkeet A.; Baker P.; Chen A.-H.; Asnir Z.Z.; Abidin Z.Z.; Hussain R.; Mokhtar A.
Published: (2018)

Platoon interactions and real-world traffic simulation and validation based on the LWRIM
by: Ng K.M.; Reaz M.B.I.
Published: (2016)

Green analytical chemistry metrics for evaluation of microextraction methods: Fascinating or essential tools in real-world applications?
by: Yahaya N.; Mohamed A.H.; Miskam M.; Abdul Keyon A.S.; Loh S.H.; Mohamad Zain N.N.; Sajid M.
Published: (2024)

Management of asthma in adults in primary care
by: Ban A.Y.-L.; Omar A.; Chong L.Y.; Lockman H.; Ida Zaliza Z.A.; Ali I.A.H.; Jaya M.; Leong S.W.; Mazapuspavina M.Y.; Yusof M.A.M.; Zim M.A.M.; Nor Azila M.I.; Jamal S.M.; Yoon C.K.; Malek Abdol Hamid Z.I.
Published: (2019)

Feasibility of implementing chronic care model in the malaysian public primary care setting
by: Ariffin F.; Ramli A.S.; Daud M.H.; Haniff J.; Abdul-Razak S.; Selvarajah S.; Lee V.; Tong S.F.; Bujang M.A.
Published: (2017)

Adherence to the Atrial Fibrillation (AF) Better Care (ABC) pathway among AF patients with heart failure (HF)
by: Zulkifly, et al.
Published: (2024)

Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study
by: Abas, et al.
Published: (2024)

Enhancing tuberculosis treatment adherence and motivation through gamified real-time mobile app utilization: a single-arm intervention study
by: Abas S.A.; Ismail N.; Zakaria Y.; Yasin S.M.; Ibrahim K.; Ismail I.; Razali A.; Sherzkawi M.A.; Ahmad N.
Published: (2024)

Case-finding and genetic testing for familial hypercholesterolaemia in primary care
by: Qureshi N.; Akyea R.K.; Dutton B.; Humphries S.E.; Hamid H.A.; Condon L.; Weng S.F.; Kai J.; Roderick P.; Neely D.; Neil A.; Williams S.; Jones M.; Walters K.; Payne K.; Hanratty B.
Published: (2021)

Cost-Effectiveness of Screening Algorithms for Familial Hypercholesterolaemia in Primary Care
by: Jones M.; Akyea R.K.; Payne K.; Humphries S.E.; Abdul-Hamid H.; Weng S.; Qureshi N.
Published: (2022)

World energy policies
by: Ilham N.I.; Hasanuzzaman M.; Mamun M.A.A.
Published: (2019)

A QOBL-SAO and its variant: An open source software for optimizing PV/wind/battery system and CEC2020 real world problems
by: Mas'ud, et al.
Published: (2024)

Sociodemographic Impact and Acquaintance on Antibiotic Resistance Among Outpatients in Specialist Hospital, Malaysia
by: Hanish Singh J.C.; Mohamed M.M.; Thayashini K.; Long C.M.; Shafeeq M.F.
Published: (2021)

Strategies for screening for familial hypercholesterolaemia in primary care and other community settings
by: Qureshi N.; Da Silva M.L.R.; Abdul-Hamid H.; Weng S.F.; Kai J.; Leonardi-Bee J.
Published: (2021)

Factors associated with anxiety among elderly hypertensive in primary care setting
by: Ismail Z.; Mohamad M.; Isa M.R.; Fadzil M.A.; Yassin S.M.; Ma K.T.; Bin Abu Bakar M.H.
Published: (2015)

Effect of standardized warfarin treatment protocol on anticoagulant effect: Comparison of a warfarin medication therapy adherence clinic with usual medical care
by: Aidit S.; Soh Y.C.; Yap C.S.; Khan T.M.; Neoh C.F.; Shaharuddin S.; Kassab Y.W.; Patel R.P.; Ming L.C.
Published: (2017)

Development and validation of a video-based intervention on self-care practices for patients with hypertension in Malaysian primary care settings
by: Raja-Ismail R.I.; Badlishah-Sham S.F.; Nik-Nasir N.M.; Isa M.R.
Published: (2024)

Does dose reduction of afatinib affect treatment outcomes of patients with EGFR-mutant metastatic non-small cell lung cancer in real-world clinical practice?
by: Poh M.E.; Chai C.S.; Liam C.K.; Ho G.F.; Pang Y.K.; Hasbullah H.H.; Tho L.M.; Nor I.M.; Ho K.F.; Thiagarajan M.; Samsudin A.; Omar A.; Ong C.K.; Soon S.Y.; Tan S.N.; How S.H.
Published: (2024)

A QOBL-SAO and its variant: An open source software for optimizing PV/wind/battery system and CEC2020 real world problems[Formula presented]
by: Mas'ud A.A.; Salawudeen A.T.; Umar A.A.; Shaaban Y.A.; Muhammad-Sukki F.; Musa U.; Alshammari S.J.
Published: (2024)

Case Series of Genetically Confirmed Index Cases of Familial Hypercholesterolemia in Primary Care
by: Kamal A.; Kanchau J.D.; Shahuri N.S.; Mohamed-Yassin M.-S.; Baharudin N.; Razak S.A.; Badlishah-Sham S.F.; Abdul-Hamid H.; Aziz A.F.A.; Al-Khateeb A.; Chua Y.A.; Kasim N.A.M.; Kadir S.H.S.A.; Nawawi H.; Qureshi N.; Ramli A.S.
Published: (2023)

Glucose Tolerance of Clostridium acetobutylicum Fermentation in the Anaerobic System
by: Fauzi B.; Nawawi M.G.M.; Fauzi R.; Ismail N.I.M.; Noor S.F.M.; Yahaya I.; Suhaimy S.H.M.; Roslan M.S.
Published: (2023)

Gender disparity in the prescription of secondary prevention medications in a Malaysian primary care clinic
by: Baharudin N.; Roslan A.M.A.; Yassin M.S.M.; Ramli A.S.; Abidin A.N.I.Z.; Sahar N.H.; Din N.S.S.; Ibrahim I.S.; Rahim S.N.H.A.; Rosli N.A.
Published: (2021)

Too enthusiastic to care for safety: Present status and recent developments of nanosafety in ASEAN countries
by: Karim M.E.; Munir A.B.; Reza A.W.; Muhammad-Sukki F.; Mohd Yasin S.H.; Abu-Bakar S.H.; Abdul Rahim R.
Published: (2015)

Current derating in fault-tolerant multiphase induction motor drives
by: Che H.S.; Tousizadeh M.; Munim W.N.W.A.; Rahim N.A.
Published: (2022)

A clinical audit of the diagnosis and management of chronic kidney disease in a primary care clinic
by: Jamaluddin J.; Yassin M.S.M.; Jamil S.N.; Kamel M.A.M.; Yusof M.Y.
Published: (2021)

Papillary Thyroid Carcinoma Presenting with Chronic Cough and Hemoptysis in Primary Care: A Case Report
by: Abd Hamid M.F.; Abdul-Razak S.; Azraai A.M.; Miptah H.N.
Published: (2023)

High prevalence of undiagnosed impaired glucose tolerance in patients with rheumatoid arthritis
by: Eddy Warman N.‘.; Baharuddin H.; Abdul Rahman T.H.; Ismail N.; Ch’Ng S.S.; Rosman A.; Abdul Ghani R.
Published: (2022)

Relationship between self-efficacy, self-care behaviour and glycaemic control among patients with type 2 diabetes mellitus in the Malaysian primary care setting
by: Tharek Z.; Ramli A.S.; Whitford D.L.; Ismail Z.; Mohd Zulkifli M.; Ahmad Sharoni S.K.; Shafie A.A.; Jayaraman T.
Published: (2018)

A Case of Linear Scleroderma in a Young Child: A Diagnosis Easily Missed in Primary Care
by: Bin Ahmad M.Z.; Mat Nasir N.; Md Yasin M.; Yusof A.N.M.; Bakrin I.H.; Lim S.C.
Published: (2023)

Health literacy-related knowledge, attitude, perceived barriers, and practice among primary care doctors in Malaysia
by: Mohamed-Yassin, et al.
Published: (2023)

A Case of Linear Scleroderma in a Young Child: A Diagnosis Easily Missed in Primary Care
by: Ahmad M.Z.B.; Nasir N.M.; Yasin M.M.; Yusof A.N.M.; Bakrin I.H.; Lim S.C.
Published: (2023)

Health literacy-related knowledge, attitude, perceived barriers, and practice among primary care doctors in Malaysia
by: Mohamed-Yassin M.-S.; Daher A.M.; Ramli A.S.; Ramli N.F.; Baharudin N.
Published: (2023)