Synthesis of novel indazole derivatives as inhibitors of diabetics II along with molecular docking and simulation study
In the light of the pharmacological significance of the indazole and 1, 3, 4-thiadiazole scaffold, hybrid analogs of indazole and 1, 3, 4-thiadiazole (1–14) were synthesized, identified using HREI-MS, 1H, and 13CNMR, and their capability for inhibition of α-amylase and α-glucosidase enzymes was eval...
Published in: | Journal of Molecular Structure |
---|---|
Main Author: | Al-Nasser F.; Taha M.; Rahim F.; Adalat B.; Chigurupati S.; Nawaz M.; Ajmal A.; Wadood A.; Uddin N.; Khan K.M.; Ali shah S.A.; Felemban S.G.; Venugopal V. |
Format: | Article |
Language: | English |
Published: |
Elsevier B.V.
2025
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85207018388&doi=10.1016%2fj.molstruc.2024.140394&partnerID=40&md5=e5be6169fdf74e8e5fb1445f9c0aed02 |
Similar Items
-
Synthesis of novel indazole derivatives as inhibitors of diabetics II along with molecular docking and simulation study
by: Al-Nasser, et al.
Published: (2025) -
Synthesis, biological evaluation and molecular docking study of indazole based schiff base analogues as new anti-diabetic inhibitors
by: Taha, et al.
Published: (2024) -
Synthesis, biological evaluation and molecular docking study of indazole based schiff base analogues as new anti-diabetic inhibitors
by: Taha M.; Gilani S.J.; Kazmi I.; Rahim F.; Adalat B.; Ullah H.; Nawaz F.; Wadood A.; Ali Z.; Shah S.A.A.; Khan K.M.
Published: (2024) -
New pyrrolopyridine-based thiazolotriazoles as diabetics inhibitors: enzymatic kinetics and in silico study
by: Taha M.; Rahim F.; Hayat S.; Chigurupati S.; Khan K.M.; Imran S.; Ali Shah S.A.; Uddin N.; Felemban S.G.; Venugopal V.
Published: (2023) -
Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study
by: Taha M.; Irshad M.; Imran S.; Chigurupati S.; Selvaraj M.; Rahim F.; Ismail N.H.; Nawaz F.; Khan K.M.
Published: (2017)