Synthesis, biological evaluation, molecular docking and dynamic simulation of novel benzofuran derivatives as potential agents against Alzheimer's disease

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Synthesis, biological evaluation, molecular docking and dynamic simulation of novel benzofuran derivatives as potential agents against Alzheimer's disease

We have synthesized novel benzofuran derivatives (1–20), characterized through different spectroscopic techniques such as 1HNMR, 13CNMR, HREI-MS and screened against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes. All derivatives showed inhibitory activities having IC50 values...

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Bibliographic Details
Published in:	Journal of Molecular Structure
Main Author:	Nadeem M.S.; Hayat S.; Rahim F.; Khan J.A.; Ullah H.; Taha M.; Gupta G.; Wadood A.; Shah S.A.A.; Kazmi I.; Iftikhar S.; Muhammad K.
Format:	Article
Language:	English
Published:	Elsevier B.V. 2025
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85206074124&doi=10.1016%2fj.molstruc.2024.140279&partnerID=40&md5=e40ae289255301808cdeec9a7a82529e

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