Synthesis, enzyme inhibitory kinetics, & computational studies of N-(substituted phenyl)-(5-(3,4-dichlorobenzyl)-4-(4-chlorophenyl)-4H-1,2,4-triazol-3-ylthio)methylbenzamides: As potent alkaline phosphatase inhibitors

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Synthesis, enzyme inhibitory kinetics, & computational studies of N-(substituted phenyl)-(5-(3,4-dichlorobenzyl)-4-(4-chlorophenyl)-4H-1,2,4-triazol-3-ylthio)methylbenzamides: As potent alkaline phosphatase inhibitors

The present research work encompass an innovative approach towards the synthesis of potent series of target compounds (8a-j) having 1,2,4-triazole and benzamide moieties as alkaline phosphatase inhibitors. The synthetic methodology was initiated by Fischer's esterification of 3,4-dichlorophenyl...

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Bibliographic Details
Published in:	Journal of Molecular Structure
Main Author:	Zeb A.; Siddiqui S.Z.; Abbasi M.A.; Aziz-ur-Rehman; Shah S.A.A.; Imran S.; Raza H.; Kim S.J.; Parveen R.; Abbas G.
Format:	Article
Language:	English
Published:	Elsevier B.V. 2025
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85204404556&doi=10.1016%2fj.molstruc.2024.139960&partnerID=40&md5=af32da6b1c2be5507643587643cb3b7e

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