HIGHER BINDING AFFINITIES OF HOPEA PHYTOCOMPOUNDS TO THE SARS-COV-2 MAIN PROTEASE THAN KNOWN ANTIVIRALS: MOLECULAR DOCKING AND DYNAMIC SIMULATION STUDY

QR Code

HIGHER BINDING AFFINITIES OF HOPEA PHYTOCOMPOUNDS TO THE SARS-COV-2 MAIN PROTEASE THAN KNOWN ANTIVIRALS: MOLECULAR DOCKING AND DYNAMIC SIMULATION STUDY

The COVID-19 pandemic has caused catastrophic worldwide, resulting in over 6.9 million reported deaths as of June 2023. While approved vaccines have significantly reduced fatalities, infections persist due to emerging SARS-CoV-2 variants. The emerging variants challenge vaccine effectiveness, prompt...

Full description

Bibliographic Details
Published in:	Journal of Engineering Science and Technology
Main Author:	Rozani N.H.A.; Jusoh S.A.; Majid F.A.A.; Mokhtar N.A.; Khairudin N.B.A.; Tap F.M.
Format:	Article
Language:	English
Published:	Taylor's University 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85204101167&partnerID=40&md5=3b1651293b4db9dbb493d34f860427ba

Similar Items

Molecular Docking of Phytochemicals from M. Charantia Targeting SARS-CoV-2 Main Protease
by: Rozani N.H.A.; Tap F.M.; Majid F.A.A.; Mokhtar N.A.; Khairudin N.B.A.
Published: (2025)

Molecular Docking and Molecular Dynamics of Herbal Plants Phylantus Niruri Linn (Green Meniran) towards of SARS-CoV-2 Main Protease
by: Fatriansyah J.F.; Kurnianto S.R.; Surip S.N.; Pradana A.F.; Boanerges A.G.
Published: (2023)

Phytochemical profiling, pharmacology prediction, and molecular docking study of Chromolaena odorata extract against multiple target proteins in wound healing
by: Mokhtar N.A.; Tap F.M.; Rozani N.H.A.; Khairudin N.B.A.; Ali R.R.
Published: (2023)

Phytochemical Study from Hopea pubescens Ridl. (Dipterocarpaceae)
by: Johari, et al.
Published: (2023)

Molecular networking-based mass spectral identification of Brucea javanica (L.) Merr. metabolites and their selective binding affinities for dengue virus enzymes
by: Yousof N.S.A.M.; Afzan A.; Zainol M.; Bakar S.I.A.; Razak M.R.M.A.; Jelas N.H.M.; Abdullah N.N.; Cordell G.A.; Ismail N.H.
Published: (2024)

Molecular networking-based mass spectral identification of Brucea javanica (L.) Merr. metabolites and their selective binding affinities for dengue virus enzymes
by: Yousof, et al.
Published: (2024)

Design of PVA/Chitosan Loaded with Chromolaena Odorata Extract as Wound Dressings
by: Mokhtar N.A.; Tap F.M.; Khairudin N.B.A.; Ali R.R.; Talib S.Z.A.
Published: (2023)

Repurposing Mitragynine as Anti-SARS-CoV-2 Agent Evidenced by In Silico Predictive Approach
by: Tap F.M.; Zakaria N.H.; Majid F.A.A.; Huq A.K.M.M.; Jamal J.A.
Published: (2022)

CHARACTERISATION OF POMACEA CANALICULATA EGGS TREATED WITH PROTEASE
by: Salleh, et al.
Published: (2024)

CHARACTERISATION OF POMACEA CANALICULATA EGGS TREATED WITH PROTEASE
by: SALLEH N.H.M.; ZAINALABIDIN N.; LATIP S.N.H.M.
Published: (2024)

Chemical and pharmacognostical characterization of two Malaysian plants both known as Ajisamat
by: Mohamad T.A.S.T.; Naz H.; Jalal R.S.; Hussin K.; Rahman M.R.A.; Adam A.; Weber J.-F.F.
Published: (2013)

Extraction of phytocompounds from the medicinal plant Clinacanthus nutans Lindau by microwave-assisted extraction and supercritical carbon dioxide extraction
by: Mustapa A.N.; Martin Á.; Mato R.B.; Cocero M.J.
Published: (2015)

Identification of Endophytic Actinomycetes Isolated From Hopea ferrea and Its Antibacterial Activity Against Cariogenic Bacterium
by: Azmin N.R.A.M.; Sarmin N.I.M.; Khan H.B.S.G.; Zainal M.
Published: (2024)

Infertile men older than 40 years are at higher risk of sperm DNA damage
by: Alshahrani S.; Agarwal A.; Assidi M.; Abuzenadah A.M.; Durairajanayagam D.; Ayaz A.; Sharma R.; Sabanegh E.
Published: (2014)

Fingerprint multiple-class classifier: performance evaluation on known and unknown fingerprint spoofing materials
by: Senanu Ametefe D.; Seroja Sarnin S.; Mohd Ali D.; John D.B.; Aliu A.A.
Published: (2024)

Evaluation of the binding interactions between Plasmodium falciparum Kelch-13 mutant recombinant proteins with artemisinin
by: Yusuf N.M.; Azman A.N.; Aziz A.A.A.; Fuad F.A.A.; Nasarudin R.N.; Hisam S.
Published: (2024)

Multimodal management of more than 50% mixed deep dermal and full thickness burns in a child
by: Subramaniam S.; Rodzaian W.S.; Yussof S.J.; Ibrahim S.; Hayati F.
Published: (2023)

Asian elephants involved in conflicts exhibit similar habitat use but travel farther than non-conflict individuals
by: Jamaluddin M.I.M.; Abidin K.Z.; Nor S.M.; Shukor A.; Zainudddin A.I.; Illias R.; Mansor M.S.
Published: (2024)

Antecedents and Consequences of Trust and Satisfaction in Main Contractor and Subcontractor Relationship
by: Rahman S.H.A.; Nusa F.N.M.; Md Hanafiah R.; Jusoh M.Z.; Endut I.R.; Faisol N.
Published: (2020)

Impact of membrane pore structure on protein detection sensitivity of affinity-based immunoassay
by: Ahmad A.L.; Ideris N.; Ooi B.S.; Low S.C.; Ismail A.
Published: (2016)

Asian elephants involved in conflicts exhibit similar habitat use but travel farther than non-conflict individuals
by: Jamaluddin, et al.
Published: (2024)

Antibacterial and Antiviral Potential of Zirconium Oxide Nanoparticle using Extract of Chloranthus erectus Leaf
by: Hasan N.A.; Wazir N.N.; Zainal-Abidin N.; Nawahwi M.Z.; Hisham N.A.B.; Yasin Y.; Masdek N.R.N.; Khairat J.E.; Yu L.Z.H.I.; Azzeme A.M.; Arief S.; Putri G.E.K.A.; Ahmad N.M.
Published: (2024)

Antiviral activity of fermented foods and their probiotics bacteria towards respiratory and alimentary tracts viruses
by: Muhialdin B.J.; Zawawi N.; Abdull Razis A.F.; Bakar J.; Zarei M.
Published: (2021)

PID controller tuning for glycerin bleaching process using well-known tuning formulas - A simulation study
by: Kamaruddin N.; Janin Z.; Yusuf Z.; Taib M.N.
Published: (2009)

PAYMENT PREDICAMENTS: EXPLORING FACTORS AND REMEDIES FOR MAIN CONTRACTOR-SUBCONTRACTOR DYNAMICS IN MALAYSIA
by: Fateh M.A.M.; Nik Mat N.A.A.; Abd Rahman R.
Published: (2024)

Neuroimaging techniques in advertising research: Main applications, development, and brain regions and processes
by: Alsharif A.H.; Salleh N.Z.M.; Baharun R.; Alharthi Rami Hashem E.; Mansor A.A.; Ali J.; Abbas A.F.
Published: (2021)

Reduction behaviors of main group and transition metals doped NiO catalysts
by: Samidin S.; Sulhadi S.S.; Lahuri A.H.; Dzakaria N.; Isahak W.N.R.W.; Jamil S.M.; Yarmo M.A.; Yusop M.R.
Published: (2024)

Phytochemical profiling of the essential oils from three Curcuma species and their in vitro and in silico dengue protease inhibition activity
by: Jani N.A.; Maarof N.I.; Zahari M.M.F.M.; Jamil M.; Zakaria I.I.; Mohamad Zobir S.Z.; Kasim N.; Salin N.H.; Mohamad Ali N.A.; Khalid W.E.F.W.; Pungot N.H.
Published: (2024)

N′-[4-[(Substituted imino)methyl]benzylidene]-substituted benzohydrazides: Synthesis, antimicrobial, antiviral, and anticancer evaluation, and QSAR studies
by: Kumar P.; Narasimhan B.; Ramasamy K.; Mani V.; Mishra R.K.; Majeed A.B.A.; De Clercq E.
Published: (2013)

A checklist of the ticks of Malaysia (Acari: Argasidae, Ixodidae), with lists of known associated hosts, geographical distribution, type localities, human infestations and pathogens
by: Kazim A.-R.; Houssaini J.; Tappe D.; Heo C.C.
Published: (2022)

Environmental degradation of structural glass systems: A review of experimental research and main influencing parameters
by: Joseph Udi U.; Yussof M.M.; Musa Ayagi K.; Bedon C.; Khairul Kamarudin M.
Published: (2023)

Peptide Cross-Linked Poly(2-oxazoline) as a Sensor Material for the Detection of Proteases with a Quartz Crystal Microbalance
by: Ahmad N.; Colak B.; Gibbs M.J.; Zhang D.-W.; Gautrot J.E.; Watkinson M.; Becer C.R.; Krause S.
Published: (2019)

The high-affinity human IgG receptor Fc gamma receptor i (FcγRI) is not associated with vascular leakage of dengue
by: Zamberi Z.M.; Zakaria Z.; Aziz A.T.A.; Heng B.S.L.; Zaid M.; Chong C.L.K.; Noor F.M.; Bakar S.A.; Peng H.B.
Published: (2015)

Targeted Isolation of Antiviral Labdane Diterpenes from the Bark of Neo-uvaria foetida (Annonaceae) using LC-MS/MS-Based Molecular Networking
by: Sukumaran S.Y.; Herrscher C.; Rasol N.E.; Othman M.A.; Liew S.Y.; Ismail N.H.; Séron K.; Litaudon M.; Awang K.; El Kalamouni C.; Apel C.; Zahari A.
Published: (2024)

Vibrio harveyi protease deletion mutant as a live attenuated vaccine candidate against vibriosis and transcriptome profiling following vaccination for Epinephelus fuscoguttatus
by: Mohd-Aris A.; Saad M.-Z.; Daud H.M.; Yusof M.T.; Ina-Salwany M.Y.
Published: (2019)

The Main Tendencies of Discourse Representation of Immigrant Workers in Malaysia: A Critical Discourse Analysis in The Star and Malaysiakini Online News Portals
by: Paridaluddin N.F.B.M.S.; Zamin A.A.B.M.
Published: (2023)

Development of a Novel CYP3A4 Classifier Model via Site of Metabolism (SOM)-based Molecular Docking, Multivariate Analysis and Molecular Dynamics of Known Substrates and Inhibitors
by: Ridhwan M.J.M.; Hashim N.A.A.; Kasim N.; Abdullah N.N.; Inayatsyah N.A.; Abid O.; Ismail N.H.; Imran S.
Published: (2024)

A comparison of assays for accurate copy number measurement of the low-affinity FC gamma receptor genes FCGR3A and FCGR3B
by: Haridan U.S.; Mokhtar U.; Machado L.R.; Aziz A.T.A.; Shueb R.H.; Zaid M.; Sim B.; Mustafa M.; Yusof N.K.N.; Lee C.K.C.; Bakar S.A.; Abubakar S.; Hollox E.J.; Peng H.B.
Published: (2015)

The Main Tendencies of Discourse Representation of Immigrant Workers in Malaysia: A Critical Discourse Analysis in The Star and Malaysiakini Online News Portals
by: Paridaluddin, et al.
Published: (2023)

Psychological Distress of Health Care Workers in the Main Admitting Hospital and Its Related Health Care Facilities in Malaysia During the COVID-19 Pandemic
by: Razali S.; Abdullah M.N.; Rahman N.A.; Azhar N.A.; Yaacob S.S.
Published: (2021)