Synthesis, Spectral Characterization, Catalytic and Antimicrobial Activities of Pd(II) and Ni(II) Schiff Base Complexes

• Published in: Malaysian Journal of Chemistry
• Main Author: Ahmad S.N.; Parumasivam T.; Nasaruddin N.H.; Khaidir S.S.
• Format: Article
• Language: English
• Published: Malaysian Institute of Chemistry 2024
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85201670073&doi=10.55373%2fmjchem.v26i4.1&partnerID=40&md5=75e82e6cc90420f2d582a136569fdaaa

Palladium(II) and nickel(II) complexes derived from aromatic Schiff bases were synthesized and characterized through physicochemical and spectroscopic analyses, viz., melting point, elemental analysis, molar conductivity, magnetic susceptibility, FTIR, UV-Vis, and 1H and 13C NMR. The shift in ν(C=N) to a lower frequency in FTIR of about 10 cm-1 indicated that complexation to Pd(II) and Ni(II) through the azomethine N was established. This was supported by the shifting of the azomethine proton signal to downfield and upfield regions in 1H NMR. In addition, the shifting of the n−π*(C=N) band in the UV-Vis spectra, with Δλ = 20−47 nm, indicated involvement of the azomethine nitrogen in the complexation. Palladium(II) complexes performed better than nickel(II) complexes as catalysts in the copper-free Sonogashira reaction, with 100 % conversion of iodobenzene in 3 hours. In the antibacterial study, L1Me showed the most promising anti-MRSA and anti-MSSA activities, with both MIC and MBC values of 3 µg/ml against the tested strains. These findings highlight the potential of Pd(II) and Ni(II) complexes as catalysts and anti-microbial agents. © 2024 Malaysian Institute of Chemistry. All rights reserved.