| Summary: | Palladium(II) and nickel(II) complexes derived from aromatic Schiff bases were synthesized and characterized through physicochemical and spectroscopic analyses, viz., melting point, elemental analysis, molar conductivity, magnetic susceptibility, FTIR, UV-Vis, and 1H and 13C NMR. The shift in ν(C=N) to a lower frequency in FTIR of about 10 cm-1 indicated that complexation to Pd(II) and Ni(II) through the azomethine N was established. This was supported by the shifting of the azomethine proton signal to downfield and upfield regions in 1H NMR. In addition, the shifting of the n−π*(C=N) band in the UV-Vis spectra, with Δλ = 20−47 nm, indicated involvement of the azomethine nitrogen in the complexation. Palladium(II) complexes performed better than nickel(II) complexes as catalysts in the copper-free Sonogashira reaction, with 100 % conversion of iodobenzene in 3 hours. In the antibacterial study, L1Me showed the most promising anti-MRSA and anti-MSSA activities, with both MIC and MBC values of 3 µg/ml against the tested strains. These findings highlight the potential of Pd(II) and Ni(II) complexes as catalysts and anti-microbial agents. © 2024 Malaysian Institute of Chemistry. All rights reserved.
|
|---|