Pyridylpiperazine-based carbodithioates as urease inhibitors: synthesis and biological evaluation

The urease enzyme is recognized as a valuable therapeutic agent for treating the virulent Helicobacter pylori bacterium because of its pivotal role in aiding the colonization and growth of the bacterium within the gastric mucosa. In order to control the harmful consequences of bacterial infections,...

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Bibliographic Details
Published in:Frontiers in Chemistry
Main Author: Akash M.; Rana N.; Aslam S.; Ahmad M.; Saif M.J.; Asghar A.; Sultan S.; Al-Hussain S.A.; Liaqat A.; Zaib S.; Zaki M.E.A.
Format: Article
Language:English
Published: Frontiers Media SA 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85201523502&doi=10.3389%2ffchem.2024.1423385&partnerID=40&md5=92cf1c4fa6f1bba9028c3af970e3556d