Evaluation of the binding interactions between Plasmodium falciparum Kelch-13 mutant recombinant proteins with artemisinin

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Evaluation of the binding interactions between Plasmodium falciparum Kelch-13 mutant recombinant proteins with artemisinin

Malaria, an ancient mosquito-borne illness caused by Plasmodium parasites, is mostly treated with Artemisinin Combination Therapy (ACT). However, Single Nucleotide Polymorphisms (SNPs) mutations in the P. falciparum Kelch 13 (PfK13) protein have been associated with artemisinin resistance (ART-R). T...

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Bibliographic Details
Published in:	PLoS ONE
Main Author:	Yusuf N.M.; Azman A.N.; Aziz A.A.A.; Fuad F.A.A.; Nasarudin R.N.; Hisam S.
Format:	Article
Language:	English
Published:	Public Library of Science 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85201370409&doi=10.1371%2fjournal.pone.0306975&partnerID=40&md5=d000c3a6f64e794164588796a321476e

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