Evaluation of the binding interactions between Plasmodium falciparum Kelch-13 mutant recombinant proteins with artemisinin

QR Code

Evaluation of the binding interactions between Plasmodium falciparum Kelch-13 mutant recombinant proteins with artemisinin

Malaria, an ancient mosquito-borne illness caused by Plasmodium parasites, is mostly treated with Artemisinin Combination Therapy (ACT). However, Single Nucleotide Polymorphisms (SNPs) mutations in the P. falciparum Kelch 13 (PfK13) protein have been associated with artemisinin resistance (ART-R). T...

Full description

Bibliographic Details
Published in:	PLoS ONE
Main Author:	Yusuf N.M.; Azman A.N.; Aziz A.A.A.; Fuad F.A.A.; Nasarudin R.N.; Hisam S.
Format:	Article
Language:	English
Published:	Public Library of Science 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85201370409&doi=10.1371%2fjournal.pone.0306975&partnerID=40&md5=d000c3a6f64e794164588796a321476e

Similar Items

Three new dihydrochalcones from the leaves of Artocarpus sericicarpus Jarrett and their activity against Plasmodium falciparum
by: Tumewu, et al.
Published: (2024)

Three new dihydrochalcones from the leaves of Artocarpus sericicarpus Jarrett and their activity against Plasmodium falciparum
by: Tumewu L.; Ilmi H.; Kartika Sari D.; Permanasari A.A.; Khairun Nisa H.; Saputri R.D.; Tjahjandarie T.S.; Tanjung M.; Osman C.P.; Ismail N.H.; Suciati; Widyawaruyanti A.; Hafid A.F.
Published: (2024)

Goniothalamin and Its Analogues as Potential Inhibitors of Plasmodium falciparum Lactate Dehydrogenase Enzyme: Molecular Docking, Molecular Dynamics Simulation Studies, and Pharmacokinetics Analysis
by: Ideris S.; Imran S.; Latip N.A.; Osman C.P.
Published: (2024)

Whole genome resequencing data and grain quality traits of the rice cultivar Mahsuri and its blast disease resistant mutant line, Mahsuri Mutant
by: Kamarudin S.A.A.; Ahmad F.; Hasan N.A.; Hisham S.N.; Yusof S.N.; Abu Hassan A.; Hussein S.; Harun A.R.; Wan Chik W.D.; Md Saad M.; Faizal Azizi M.M.; Abd Aziz Shamsudin N.
Published: (2024)

Optimization of polyvinylidene fluoride (PVDF) membrane fabrication for protein binding using statistical experimental design
by: Ahmad A.L.; Ideris N.; Ooi B.S.; Low S.C.; Ismail A.
Published: (2016)

Plasmodium spp. in macaques, Macaca fascicularis, in Malaysia, and their potential role in zoonotic malaria transmission
by: Yusuf N.M.; Zulkefli J.; Jiram A.I.; Vythilingam I.; Hisam S.; Devi R.; Salehhuddin A.; Ali N.M.; Isa M.; Alias N.; Salim N.O.; Aziz A.A.; Sulaiman L.H.
Published: (2022)

HIGHER BINDING AFFINITIES OF HOPEA PHYTOCOMPOUNDS TO THE SARS-COV-2 MAIN PROTEASE THAN KNOWN ANTIVIRALS: MOLECULAR DOCKING AND DYNAMIC SIMULATION STUDY
by: Rozani N.H.A.; Jusoh S.A.; Majid F.A.A.; Mokhtar N.A.; Khairudin N.B.A.; Tap F.M.
Published: (2024)

Analysis of expression of vitamin E-binding proteins in H2O2induced SK-N-SH neuronal cells supplemented with α-tocopherol and tocotrienol-rich fraction
by: Chiroma A.A.; Khaza'ai H.; Hamid R.A.; Chang S.K.; Zakaria Z.A.; Zainal Z.
Published: (2020)

Genetic polymorphism and natural selection in the C-terminal 42 kDa region of merozoite surface protein-1 (MSP-1) among Plasmodium knowlesi samples from Malaysia 06 Biological Sciences 0604 Genetics
by: Yap N.J.; Vythilingam I.; Hoh B.P.; Goh X.T.; Muslim A.; Ngui R.; Rajoo Y.; Choy S.H.; William T.; Yeo T.W.; Lim Y.A.-L.
Published: (2018)

Vibrio harveyi protease deletion mutant as a live attenuated vaccine candidate against vibriosis and transcriptome profiling following vaccination for Epinephelus fuscoguttatus
by: Mohd-Aris A.; Saad M.-Z.; Daud H.M.; Yusof M.T.; Ina-Salwany M.Y.
Published: (2019)

Composition of overlapping protein-protein and protein-ligand interfaces
by: Mohamed R.; Degac J.; Helms V.
Published: (2015)

Invasion characteristics of a Plasmodium knowlesi line newly isolated from a human
by: Amir A.; Russell B.; Liew J.W.K.; Moon R.W.; Fong M.Y.; Vythilingam I.; Subramaniam V.; Snounou G.; Lau Y.L.
Published: (2016)

Characterisation of Plasmodium berghei NK65 Infection in ICR Mice as a Severe Malarial Infection Model; [Pencirian Jangkitan Plasmodium berghei NK65 pada Mencit ICR sebagai Model Jangkitan Malaria Teruk]
by: Ali A.H.; Hassan W.R.M.; Dahari D.E.; Embi N.; Sidek H.M.; Basir R.; Agustar H.K.; Latip J.
Published: (2022)

Does dose reduction of afatinib affect treatment outcomes of patients with EGFR-mutant metastatic non-small cell lung cancer in real-world clinical practice?
by: Poh M.E.; Chai C.S.; Liam C.K.; Ho G.F.; Pang Y.K.; Hasbullah H.H.; Tho L.M.; Nor I.M.; Ho K.F.; Thiagarajan M.; Samsudin A.; Omar A.; Ong C.K.; Soon S.Y.; Tan S.N.; How S.H.
Published: (2024)

Natural human infections with Plasmodium cynomolgi, P. inui, and 4 other Simian Malaria Parasites, Malaysia
by: Yap N.J.; Hossain H.; Nada-Raja T.; Ngui R.; Muslim A.; Hoh B.-P.; Khaw L.T.; Kadir K.A.; Simon Divis P.C.; Vythilingam I.; Singh B.; Lim Y.A.-L.
Published: (2021)

Computational analysis of protein–protein interactions in motile T-cells
by: Kumar S.; Fazil M.H.U.T.; Ahmad K.; Tripathy M.; Rajapakse J.C.; Verma N.K.
Published: (2019)

Optimization of CTLA-4 and PD-1 proteins in EMT6 Mouse Mammary Cancer Cells by Western Blot
by: Sham N.F.R.; Hasani N.A.H.; Idorus M.Y.; Karim M.K.A.; Fuad S.B.S.A.; Hasbullah H.H.; Ibahim M.J.
Published: (2023)

Primaquine and chloroquine nano-sized solid dispersion-loaded dissolving microarray patches for the improved treatment of malaria caused by Plasmodium vivax
by: Anjani Q.K.; Volpe-Zanutto F.; Hamid K.A.; Sabri A.H.B.; Moreno-Castellano N.; Gaitán X.A.; Calit J.; Bargieri D.Y.; Donnelly R.F.
Published: (2023)

In Silico Elucidation of Protein-Protein Interaction Network in Fish Pathogen Flavobacterium columnare
by: Nematiasgarabad P.; Hashim N.A.N.; Yahya M.F.Z.R.
Published: (2024)

In Silico Elucidation of Protein-Protein Interaction Network in Fish Pathogen Flavobacterium columnare
by: Nematiasgarabad, et al.
Published: (2024)

The exposure of media frames among Malaysian bloggers pre and post 13th general election; [Pendedahan bingkai media dalam kalangan blogger di Malaysia sebelum dan selepas pru ke-13]
by: Abdullah M.H.T.; Ahmad A.L.; Kee C.P.
Published: (2016)

Angiotensin converting enzyme 2 in the gastrointestinal tract: binding with coronavirus and its consequences
by: Khan J.; Zain W.N.W.M.; Islam M.N.
Published: (2022)

IN SILICO AND MS/MS-BASED APPROACHES TO INVESTIGATE PROTEIN-PROTEIN INTERACTION NETWORKS IN Staphylococcus aureus BIOFILM; [Pendekatan Berasaskan In Silico dan MS/MS Untuk Mengkaji Jaringan Interaksi Protein-Protein dalam Biofilem Staphylococcus aureus]
by: Zulkiply N.; Yunus N.M.; Idris H.; Noor W.S.A.W.M.; Karsani S.A.; Yahya M.F.Z.R.
Published: (2024)

Computational approaches: Discovery of GTPase HRas as prospective drug target for 1,3-diazine scaffolds
by: Kumar S.; Sharma D.; Narasimhan B.; Ramasamy K.; Shah S.A.A.; Lim S.M.; Mani V.
Published: (2019)

Surface morphology and Si 2p binding energy investigation of multilayer porous silicon nanostructure
by: Radzi A.A.S.M.; Yarmo M.A.; Rusop M.; Abdullah S.
Published: (2013)

Enhancement of myofibrillar protein gelation by plant proteins for improved surimi gel characteristics: Mechanisms and performance
by: Zhao Y.; Wei K.; Chen J.; Wei G.; Li J.; Zheng B.; Song Y.; Gao P.; Zhou R.
Published: (2024)

Novel thiosemicarbazide-oxadiazole hybrids as unprecedented inhibitors of yeast α-glucosidase and in silico binding analysis
by: Taha M.; Ismail N.H.; Imran S.; Wadood A.; Ali M.; Rahim F.; Khan A.A.; Riaz M.
Published: (2016)

Current analysis on 1,3-propanediol production from glycerol via pure wild strain fermentation
by: Tey K.Y.; Tan J.P.; Yeap S.K.; He N.; Bukhari N.A.; Hui Y.W.; Luthfi A.A.I.; Abdul Manaf S.F.
Published: (2023)

Mechanical Behaviour Slenderness Ratio of 13 Solid Wall Panels Under Uniformly Distributed Load
by: Ruslan, et al.
Published: (2024)

Data mining framework for protein function prediction
by: Rahman S.A.; Hussein Z.A.M.; Bakar A.A.
Published: (2008)

In silico binding analysis and SAR elucidations of newly designed benzopyrazine analogs as potent inhibitors of thymidine phosphorylase
by: Taha M.; Ismail N.H.; Imran S.; Rahim F.; Wadood A.; Al Muqarrabun L.M.R.; Khan K.M.; Ghufran M.; Ali M.
Published: (2016)

Accuracy Assessment on Detail Survey Plan Using iPhone 13 Pro Max LiDAR Sensor
by: Nik Azhan Hakim N.N.A.; Razali R.; Mohd Said M.S.; Muhamad M.A.H.; Abdul Rahim H.; Mokhtar M.A.
Published: (2023)

Fibrous oil palm frond as a potential microbial immobilization carrier for enhanced 1,3-propanediol productivity
by: Tey K.Y.; Luthfi A.A.I.; Manaf S.F.A.; Mong G.R.; Woon K.S.; Yeap S.K.; Mahmod S.S.; Jamali N.S.; Tan J.P.
Published: (2024)

Physicochemical, in vitro bile-acid binding and hypoglycaemic properties of red pitaya (Hylocereus polyrhizus) peel pectin
by: Al-Ezzi M.; Muhammad K.; Gannasin S.P.; Hamzah M.Y.; Shukri R.; Carew I.
Published: (2024)

Protein intake recommendation for stunted children: An-update review
by: Fikri A.M.; Astuti W.; Nurhidayati V.A.; Puspita Prameswari F.S.; Hadi Ismail N.
Published: (2024)

Spermatozoa protein alterations in infertile men with bilateral varicocele
by: Agarwal A.; Sharma R.; Durairajanayagam D.; Cui Z.; Ayaz A.; Gupta S.; Willard B.; Gopalan B.; Sabanegh E.
Published: (2016)

Survey on serum protein electrophoresis and recommendations for standardised reporting
by: Sthaneshwar P.; Thambiah S.C.; Mat Salleh M.J.; Nasuruddin D.N.; Ahmad Zabidi N.F.; Jelani A.M.; Ismail A.M.; Lai L.C.; Gan G.G.
Published: (2021)

CRL4Cdt2 Ubiquitin Ligase, A Genome Caretaker Controlled by Cdt2 Binding to PCNA and DNA
by: Mazian M.A.; Yamanishi K.; Rahman M.Z.A.; Ganasen M.; Nishitani H.
Published: (2022)

CRC13: Management of Snoring with Novel Mandibular Advancement Device in a Bruxing Patient: A Case Report
by: Kashmoola S.; Ariff T.F.T.M.; Shoji Y.
Published: (2018)

Fibrous oil palm frond as a potential microbial immobilization carrier for enhanced 1,3-propanediol productivity
by: Tey, et al.
Published: (2024)