Inhibition of angiogenesis and metastasis in colorectal cancer cell lines through KRAS-associated signaling pathways by 2-methoxy-6-undecyl-1,4-benzoquinone

QR Code

Inhibition of angiogenesis and metastasis in colorectal cancer cell lines through KRAS-associated signaling pathways by 2-methoxy-6-undecyl-1,4-benzoquinone

Colorectal cancer (CRC), the third most prevalent cancer globally, presents formidable hurdles in treatment owing to factors such as therapeutic resistance and genetic mutations affecting primary drug targets. 2-methoxy-6-undecyl-1,4-benzoquinone (BQ), derived from Ardisia crispa roots, has emerged...

Full description

Bibliographic Details
Published in:	Chemico-Biological Interactions
Main Author:	Abd Rahman N.I.; Tham C.L.; Abd Hamid R.
Format:	Article
Language:	English
Published:	Elsevier Ireland Ltd 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198720556&doi=10.1016%2fj.cbi.2024.111151&partnerID=40&md5=ec0a5859180218686351dbb27ba059eb

Similar Items

Chemoprevention by Microencapsulated Lactiplantibacillus Plantarum LAB12 Against Orthotopic Colorectal Cancer Mice is Associated with Apoptosis and Anti-angiogenesis
by: Fareez I.M.; Lim S.M.; Ramasamy K.
Published: (2024)

Design, synthesis, antimicrobial and cytotoxicity study on human colorectal carcinoma cell line of new 4,4′-(1,4-phenylene) bis(pyrimidin-2-amine) derivatives
by: Kumar S.; Lim S.M.; Ramasamy K.; Mani V.; Shah S.A.A.; Narasimhan B.
Published: (2018)

Prostatic Metastasis Mimicking a Ligamentum Flavum Cyst in Thoracic Spine: A Case Report
by: Choong C.L.; Lee C.K.; Thamasegaran K.; Choy K.W.
Published: (2023)

Targeting signaling pathways with andrographolide in cancer therapy (Review)
by: Shaharudin N.S.; Singh G.K.S.; Kek T.L.; Sultan S.
Published: (2024)

Establishment of humanised xenograft models as in vivo study for lung metastasis of osteosarcoma
by: Khamarudin F.; Muhamad M.; Ibahim M.J.; I’zzah Wan Mohamad Zain W.N.; Aziz M.A.; Adib Ridzuan N.R.; Ab-Rahim S.
Published: (2024)

Genoprotective potential of Macaranga species phytochemical compounds on HT-29 human colorectal adenocarcinoma cell line
by: Siew E.L.; Pearanpan L.; Zamkhuri Z.; Nordin F.J.; Ooi T.C.; Chan K.M.; Kamarozaman A.S.; Ahmat N.; Rajab N.F.
Published: (2023)

Sound Vibration Signal Enhancement for Bearing Fault Detection by Using Adaptive Filter: Adaptive Noise Canceling and Adaptive Line Enhancer
by: Sheikh Abdul Nasir S.M.F.; Abd Wahid K.A.; Farhan Saniman M.N.; Wan Muhammad W.M.; Abdul Rahim I.
Published: (2022)

(E)-2-Methoxy-N'-(2,4,6-trihydroxybenzylidene)benzohydrazide
by: Taha M.; Baharudin M.S.; Ismail N.H.; Shah S.A.A.; Yousuf S.
Published: (2013)

Convolutional Neural Network for Transmission Line Fault Diagnosis Based on Signal Segmentation Approach
by: Omar A.M.S.; Samat A.A.A.; Faisal F.; Osman M.K.; Ibrahim M.N.; Hussain Z.
Published: (2023)

The Standardized Extract of Centella asiatica and Its Fractions Exert Antioxidative and Anti-Neuroinflammatory Effects on Microglial Cells and Regulate the Nrf2/HO-1 Signaling Pathway
by: Hambali, et al.
Published: (2024)

Hepatoid adenocarcinoma of the lung with hard palate metastasis: Review of a rare presentation of lung cancer
by: Shahrudin, et al.
Published: (2023)

Eurycomanone and eurycomanol from Eurycoma longifolia jack as regulators of signaling pathways involved in proliferation, cell death and inflammation
by: Hajjouli S.; Chateauvieux S.; Teiten M.-H.; Orlikova B.; Schumacher M.; Dicato M.; Choo C.-Y.; Diederich M.
Published: (2014)

P-Methoxy Azobenzene Terpolymer as a Promising Energy-Storage Liquid Crystal System
by: Ibrahim A.R.; Khyasudeen M.F.; Husband J.; Alauddin S.M.; Aripin N.F.K.; Velayutham T.S.; Martinez-Felipe A.; Abou-Zied O.K.
Published: (2021)

Diazenyl schiff bases: Synthesis, spectral analysis, antimicrobial studies and cytotoxic activity on human colorectal carcinoma cell line (HCT-116)
by: Kaur H.; Lim S.M.; Ramasamy K.; Vasudevan M.; Shah S.A.A.; Narasimhan B.
Published: (2020)

Crystal structure of bis(2-methoxy-6-((Z)-(p-tolylimino)methyl)phenoxy)palladium
by: Kassim K.; Kahar M.A.M.; Yamin B.M.; Manan M.A.F.A.; Yusof M.S.M.
Published: (2019)

Aloe emodin induces apoptosis in ER+-breast cancer cells; MCF-7 through IGF-1R signalling pathway
by: Amin I.M.; Kamaludin R.; Yeap S.K.; Isa M.R.; Mohd Rosdy N.M.M.N.; Siran R.; Kadir S.H.S.A.; Hasani N.A.H.
Published: (2015)

Hybrid signal processing and machine learning algorithm for adaptive fault classification of wind farm integrated transmission line protection
by: Emmanue O.; Othman M.L.; Hizam H.; Othman M.M.; Aker E.; Okeke Chidiebere A.; Samuel T.N.
Published: (2019)

OPTIMIZED SAMPLE PREPARATION TECHNIQUE FOR VISUALISATION OF THE ADHERENCE OF LACTOBACILLACEAE SP. TO HUMAN COLORECTAL ADENOCARCINOMA CELL LINE HT-29 BY FIELD EMISSION SCANNING ELECTRON MICROSCOPE
by: Ilyanie H.Y.; Muryany I.M.Y.; Huda-Faujan N.
Published: (2023)

[3-Methoxy-5-(methoxycarbonyl)isoxazol-4-yl](4-methoxyphenyl)iodonium 2,2,2-trifluoroacetate
by: Manan M.A.F.A.; Cordes D.B.; Slawin A.M.Z.; O’Hagan D.
Published: (2023)

Protective Effect of Natural Products Against Cisplatin-Induced DNA Damage in Kidney and Liver via Its Signalling Transduction Pathways: A Review
by: Zulfikri N.I.Z.; Choy K.W.; Satar N.A.; Hussan F.; Ridzuan N.R.A.
Published: (2024)

Role of TGF-β1/SMADs signalling pathway in resveratrol-induced reduction of extracellular matrix deposition by dexamethasone-treated human trabecular meshwork cells
by: Bakar A.S.A.; Razali N.; Agarwal R.; Iezhitsa I.; Perfilev M.A.; Vassiliev P.M.
Published: (2024)

The Standardized Extract of Centella asiatica and Its Fractions Exert Antioxidative and Anti-Neuroinflammatory Effects on Microglial Cells and Regulate the Nrf2/HO-1 Signaling Pathway
by: Hambali A.; Jusril N.A.; Hashim N.F.Md.; Manan N.A.; Adam S.K.; Mehat M.Z.; Adenan M.I.; Stanslas J.; Hamid H.A.
Published: (2024)

An efficient EYDFA with a 54 dB small signal gain
by: Muhd-Yassin S.Z.; Harun S.W.; Abdul-Rashid H.A.; Abd-Rahman M.K.; Abd Rahman F.; Ahmad H.
Published: (2007)

Transmission Line Measurement for Characterization of New Textile Sample
by: Abd Rahman N.H.; Yamada Y.; Zulkipli M.S.; Shakir Amin Nordin M.
Published: (2019)

Kaempferol and chrysin synergies to improve septic mice survival
by: Harasstani O.A.; Tham C.L.; Israf D.A.
Published: (2017)

Dysbiosis and the Chemopreventive Role of Prebiotics in Colorectal Cancer
by: Fareez I.M.; Haque N.; Al-Namnam N.M.; Seng W.Y.; Shafiq A.; Ismail M.I.; Meng L.S.; Ramasamy K.
Published: (2023)

Acquired radioresistance in EMT6 mouse mammary carcinoma cell line is mediated by CTLA-4 and PD-1 through JAK/STAT/PI3K pathway
by: Sham N.F.R.; Hasani N.A.H.; Hasan N.; Karim M.K.A.; Fuad S.B.S.A.; Hasbullah H.H.; Ibahim M.J.
Published: (2023)

Correction to: The role of blockchain to secure internet of medical things (Scientific Reports, (2024), 14, 1, (18422), 10.1038/s41598-024-68529-x)
by: Ghadi Y.Y.; Mazhar T.; Shahzad T.; Amir khan M.; Abd‑Alrazaq A.; Ahmed A.; Hamam H.
Published: (2024)

Tips for safety in endoscopic submucosal dissection for colorectal tumors
by: Yoshida N.; Naito Y.; Murakami T.; Hirose R.; Ogiso K.; Inada Y.; Rani R.A.; Kishimoto M.; Nakanishi M.; Itoh Y.
Published: (2017)

Spatial analysis of colorectal cancer cases in Kuala Lumpur
by: Shah S.A.; Neoh H.-M.; Rahim S.S.S.A.; Azhar Z.I.; Hassan M.R.; Safian N.; Jamal R.
Published: (2014)

Centella asiatica protects D-galactose/AlCl3 mediated alzheimer’s disease-like rats via PP2A/GSK-3β signaling pathway in their hippocampus
by: Chiroma S.M.; Baharuldin M.T.H.; Taib C.N.M.; Amom Z.; Jagadeesan S.; Adenan M.I.; Mahdi O.; Moklas M.A.M.
Published: (2019)

Osteoblast Demineralization Induced by Oxidized High-Density Lipoprotein via the Inflammatory Pathway Is Suppressed by Adiponectin
by: Harun N.H.; Froemming G.R.A.; Mohd Ismail A.; Nawawi H.; Mokhtar S.S.; Abd Muid S.
Published: (2022)

Insight parameter drug design for human β-tryptase inhibition integrated molecular docking, QSAR, molecular dynamics simulation, and pharmacophore modelling studies of α-keto-[1,2,4]-oxadiazoles
by: Yu C.X.; Tan J.W.; Rullah K.; Imran S.; Tham C.L.
Published: (2023)

YOLO and residual network for colorectal cancer cell detection and counting
by: Haq, et al.
Published: (2024)

YOLO and residual network for colorectal cancer cell detection and counting
by: Haq I.; Mazhar T.; Asif R.N.; Ghadi Y.Y.; Ullah N.; Khan M.A.; Al-Rasheed A.
Published: (2024)

Changes in electrical properties of MOS transistor induced by single 14 MeV neutron
by: Haider F.A.; Chee F.P.; Abu Hassan H.; Saafie S.; Afishah A.
Published: (2016)

Malaysia's 14th General Election via Twitter: An analysis using the epidemiological model
by: Noor N.S.M.; Akil K.A.K.; Shafie L.A.
Published: (2019)

The Effect of Orifice Diameter to the Acoustic Signals Captured at the Cold Part of a Ranque-Hilsch Vortex Tube
by: Wisnoe W.; Abd Rahman K.M.; Istihat Y.; Natarajan V.D.
Published: (2017)

Multiple primary malignant tumours of lung and colorectal adenocarcinoma: A case report
by: Ibrahim M.A.; Dashuki N.; Mohd Noor N.; Rusli S.M.
Published: (2023)

TCGA-My: A Systematic Repository for Systems Biology of Malaysian Colorectal Cancer
by: Azuwar M.A.; Muhammad N.A.N.; Afiqah-Aleng N.; Mutalib N.-S.A.; Yusof N.F.M.; Yunos R.I.M.; Ishak M.; Saidin S.; Rose I.M.; Sagap I.; Mazlan L.; Azman Z.A.M.; Mazlan M.; Rahim S.A.; Ngah W.Z.W.; Nathan S.; Hashim N.A.A.; Mohamed-Hussein Z.-A.; Jamal R.
Published: (2022)