MEMBRANE-PROTECTED MICRO-SOLID PHASE EXTRACTION OF CARCINOGENIC AROMATIC AMINES IN WATER SAMPLES PRIOR TO GC-FID ANALYSIS; [Pengekstrakan Fasa Pepejal Mikro Yang Dilindungi oleh Membran untuk Amin Aromatik Karsinogenik dalam Sampel Air dengan Analisis GC-FID]

• Published in: Malaysian Journal of Analytical Sciences
• Main Author: Patabendi A.P.; Shahriman M.S.; Surikumaran H.; Zain N.N.M.; Yahaya N.; Yunus F.M.; Usman U.A.; Sambasevam K.P.; Raoov M.
• Format: Article
• Language: English
• Published: Malaysian Society of Analytical Sciences 2024
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198618149&partnerID=40&md5=ddcc55dd681bc863a8e825f501ade6e8

A simple method to extract aromatic amines in environmental water samples was developed using β-cyclodextrin-toluene diisocyanate (β-CD-TDI) polymer enclosed with tea bag filter paper fashioned as a micro-solid phase extraction (µ-SPE) device combined with GC-FID. In this study, an efficient sorbent (β-CD-TDI polymer) was successfully synthesised and characterizaed for the microextraction of aromatic amines such as p-Toluidine, 4-chloroaniline, 2-naphthylamine, and 4-aminobiphenyl using FTIR, FESEM and TGA. Under optimized conditions (40 mg of β-CD-TDI polymer in 5 mL sample volume with 75 min extraction time and desorption with 300 µL of acetonitrile under 30s desorption time), β-CD-TDI polymer was proven to be an effective adsorbent for the extraction of aromatic amines in environmental water samples with a satisfactory percentage recovery achieved from 80 to 99%. All the studied analytes showed good linearity in the range of 5 to 500 µg L-1 and the correlation of determination (R2) was from 0.9980 to 0.9990. The LODs obtained were from 1.67 to 3.18 µg L-1, and LOQs were from 5.05 to 9.63 µg L-1. This method gives precision values for both intra-and inter-day within accepted variable limits (<15% of RSD). The self-made cellulose-based μ-SPE device revealed that it can be simply prepared, easy to operate, reusable, cost-effective, reduce chemical consumption during extraction, and additionally speed up the extraction process, making it more efficient. © 2024, Malaysian Society of Analytical Sciences. All rights reserved.