Characteristics of calcified nodule attributable to culprit lesion in acute coronary syndrome: A systematic review and meta-analysis
The presence of calcified nodule (CN) is a significant characteristic of atherothrombosis in acute coronary syndrome (ACS). However, its characteristics continue to be understudied. This review aimed to further investigate these characteristics. This study found that CN was a distinctive feature of...
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2024
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2-s2.0-85198161503 Kurniawan R.B.; Saputra P.B.T.; Haq A.U.D.U.; Purwati D.D.; Wungu C.D.K.; Susilo H.; Alsagaff M.Y.; Amin I.M.; Oktaviono Y.H. Characteristics of calcified nodule attributable to culprit lesion in acute coronary syndrome: A systematic review and meta-analysis 2024 iScience 27 7 10.1016/j.isci.2024.110351 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198161503&doi=10.1016%2fj.isci.2024.110351&partnerID=40&md5=9b811d37a69ca531905e45a10bbfe1a1 The presence of calcified nodule (CN) is a significant characteristic of atherothrombosis in acute coronary syndrome (ACS). However, its characteristics continue to be understudied. This review aimed to further investigate these characteristics. This study found that CN was a distinctive feature of an atheromatous plaque, representing 6.3% of ACS. CN was more common in NSTE-ACS than in STEMI patients (9.4% vs. 6.6%). CN was also chiefly observed in the left anterior descendant artery (48%), followed by the right coronary (40.4%) and left circumflex (14.5%) arteries. Higher prevalence of hypertension (78.8%), diabetes mellitus (50.8%), multivessel disease (71.7%), and kidney disease (26.43%) were noted in CN compared to non-CN patients. CN-associated ACS also 6-fold increased the risk of target lesion revascularization compared to those without CN. © 2024 The Authors Elsevier Inc. 25890042 English Article All Open Access; Gold Open Access |
author |
Kurniawan R.B.; Saputra P.B.T.; Haq A.U.D.U.; Purwati D.D.; Wungu C.D.K.; Susilo H.; Alsagaff M.Y.; Amin I.M.; Oktaviono Y.H. |
spellingShingle |
Kurniawan R.B.; Saputra P.B.T.; Haq A.U.D.U.; Purwati D.D.; Wungu C.D.K.; Susilo H.; Alsagaff M.Y.; Amin I.M.; Oktaviono Y.H. Characteristics of calcified nodule attributable to culprit lesion in acute coronary syndrome: A systematic review and meta-analysis |
author_facet |
Kurniawan R.B.; Saputra P.B.T.; Haq A.U.D.U.; Purwati D.D.; Wungu C.D.K.; Susilo H.; Alsagaff M.Y.; Amin I.M.; Oktaviono Y.H. |
author_sort |
Kurniawan R.B.; Saputra P.B.T.; Haq A.U.D.U.; Purwati D.D.; Wungu C.D.K.; Susilo H.; Alsagaff M.Y.; Amin I.M.; Oktaviono Y.H. |
title |
Characteristics of calcified nodule attributable to culprit lesion in acute coronary syndrome: A systematic review and meta-analysis |
title_short |
Characteristics of calcified nodule attributable to culprit lesion in acute coronary syndrome: A systematic review and meta-analysis |
title_full |
Characteristics of calcified nodule attributable to culprit lesion in acute coronary syndrome: A systematic review and meta-analysis |
title_fullStr |
Characteristics of calcified nodule attributable to culprit lesion in acute coronary syndrome: A systematic review and meta-analysis |
title_full_unstemmed |
Characteristics of calcified nodule attributable to culprit lesion in acute coronary syndrome: A systematic review and meta-analysis |
title_sort |
Characteristics of calcified nodule attributable to culprit lesion in acute coronary syndrome: A systematic review and meta-analysis |
publishDate |
2024 |
container_title |
iScience |
container_volume |
27 |
container_issue |
7 |
doi_str_mv |
10.1016/j.isci.2024.110351 |
url |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198161503&doi=10.1016%2fj.isci.2024.110351&partnerID=40&md5=9b811d37a69ca531905e45a10bbfe1a1 |
description |
The presence of calcified nodule (CN) is a significant characteristic of atherothrombosis in acute coronary syndrome (ACS). However, its characteristics continue to be understudied. This review aimed to further investigate these characteristics. This study found that CN was a distinctive feature of an atheromatous plaque, representing 6.3% of ACS. CN was more common in NSTE-ACS than in STEMI patients (9.4% vs. 6.6%). CN was also chiefly observed in the left anterior descendant artery (48%), followed by the right coronary (40.4%) and left circumflex (14.5%) arteries. Higher prevalence of hypertension (78.8%), diabetes mellitus (50.8%), multivessel disease (71.7%), and kidney disease (26.43%) were noted in CN compared to non-CN patients. CN-associated ACS also 6-fold increased the risk of target lesion revascularization compared to those without CN. © 2024 The Authors |
publisher |
Elsevier Inc. |
issn |
25890042 |
language |
English |
format |
Article |
accesstype |
All Open Access; Gold Open Access |
record_format |
scopus |
collection |
Scopus |
_version_ |
1812871794647891968 |