Synthesis, Crystal Structure, Anticancer Evaluation and Hirshfeld Surface Analysis of Novel Antipyrine Gathered Bis-Triazoles as Breast Adenocarcinoma Inhibitors

QR Code

Synthesis, Crystal Structure, Anticancer Evaluation and Hirshfeld Surface Analysis of Novel Antipyrine Gathered Bis-Triazoles as Breast Adenocarcinoma Inhibitors

Abstract: A series of novel substituted antipyrine attached bis-triazoles 7(a-h) were synthesized via coupling followed by click chemistry reaction. Their structure was established by means of physico-chemical spectral studies and a single-crystal X-ray diffraction analysis (7c and 7f). X-ray diffra...

Full description

Bibliographic Details
Published in:	Journal of Structural Chemistry
Main Author:	Beliyaiah L.; Anil Kumar G.N.; Tajuddin A.M.; Javarappa R.; Kumaraswamy M.; Basavaraju Y.B.
Format:	Article
Language:	English
Published:	Pleiades Publishing 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198058358&doi=10.1134%2fS002247662406012X&partnerID=40&md5=d78951825b9390e7f4ba72b13d263d88

Similar Items

Crystal engineering with novel antipyrine derivatives: Insights from X-ray diffraction, Hirshfeld surface analysis, and DFT calculations on intermolecular interactions
by: Rocha M.; Saeed A.; Gil D.M.; Echeverría G.A.; Piro O.E.; Khurshid A.; Arshad M.; Shah S.A.A.; Erben M.F.
Published: (2025)

Crystal engineering with novel antipyrine derivatives: Insights from X-ray diffraction, Hirshfeld surface analysis, and DFT calculations on intermolecular interactions
by: Rocha, et al.
Published: (2025)

Synthesis, crystal structure, photophysical properties, DFT studies and Hirshfeld surface analysis of a phosphorescent 1,2,4-triazole-based iridium(III) complex
by: Bain N.H.A.S.; Ali N.M.; Juahir Y.; Hashim N.; Isa I.M.; Mohamed A.; Kamari A.; Anouar E.H.; Yamin B.M.; Tajuddin A.M.; Baharudin M.H.
Published: (2020)

Crystal structure of 2,2'-(((2,2-dimethylpropane-1,3-diyl)bis(azanylylidene))- bis(methanylylidene))bis(4-methoxyphenol)palladium(II)
by: Ahmad S.N.; Bahron H.; Tajuddin A.M.; Sukeri M.M.Y.
Published: (2017)

Reactions of Ru3(CO)12 with 1,5-bis(diphenylphosphino)pentane: Synthesis, characterization, crystal structure, Hirshfeld surface and QTAIM Analysis of Ru3(CO)10(µ-dpppe)
by: Sirat S.S.; Rosli M.M.; Arshad S.; Al‐Ibadi M.A.M.; Hassan A.H.; Yusof E.N.M.; Shawkataly O.B.
Published: (2025)

Reactions of Ru3(CO)12 with 1,5-bis(diphenylphosphino)pentane: Synthesis, characterization, crystal structure, Hirshfeld surface and QTAIM Analysis of Ru3(CO)10(μ-dpppe)
by: Sirat, et al.
Published: (2025)

Krukenberg tumour as the initial manifestation of lung adenocarcinoma
by: Lim G.Y.; Wong Y.S.; Tawil Z.; Abdul Kadir R.F.; Ramanathan A.; Natasya Musa A.
Published: (2023)

Krukenberg tumor as the initial manifestation of lung adenocarcinoma
by: Wong, et al.
Published: (2023)

The Elusive Primary: Metastatic Adenocarcinoma of the Breast Presenting Solely as a Hard Sternal Mass
by: Omar R.M.; Ismail I.A.; Yasin M.M.; Affandi K.A.; Hasbullah H.H.; Ali N.D.M.
Published: (2023)

Crystal structure of bis(2-methoxy-6-((Z)-(p-tolylimino)methyl)phenoxy)palladium
by: Kassim K.; Kahar M.A.M.; Yamin B.M.; Manan M.A.F.A.; Yusof M.S.M.
Published: (2019)

Coupling efficiency of polymer optical fiber for light-gathering power in optical fiber daylighting system
by: Sulaiman F.; Ahmad A.; Ahmed A.Z.
Published: (2003)

Aggressive recurrent urachal adenocarcinoma: A case report and review of the literature
by: Abidin Z.A.Z.; Sultan M.A.H.; Hayati F.; Zainuddin Z.
Published: (2021)

Multiple primary malignant tumours of lung and colorectal adenocarcinoma: A case report
by: Ibrahim M.A.; Dashuki N.; Mohd Noor N.; Rusli S.M.
Published: (2023)

The importance of keeping alive sustainable foraging practices: Wild vegetables and herbs gathered by Afghan refugees living in Mansehra District, Pakistan
by: Manduzai A.K.; Abbasi A.M.; Khan S.M.; Abdullah A.; Prakofjewa J.; Amini M.H.; Amjad M.S.; Cianfaglione K.; Fontefrancesco M.F.; Soukand R.; Pieroni A.
Published: (2021)

Hepatoid adenocarcinoma of the lung with hard palate metastasis: Review of a rare presentation of lung cancer
by: Shahrudin, et al.
Published: (2023)

Synthesis, crystal structure and Hirshfeld surface analysis of ethyl 4-hydroxy-2-(4-hydroxyphenyl)-1-methyl-5-oxo-2,5-dihydro1H-pyrrole-3-carboxylate
by: Rashid, et al.
Published: (2023)

SPECTROSCOPIC, CRYSTAL STRUCTURE, HIRSHFELD SURFACE AND DFT STUDIES OF 2-AMINO-4-CHLOROBENZONITRILE; [Kajian Spektroskopi, Struktur Hablur, Permukaan Hirsfeld dan DFT bagi 2-Amino-4-Klorobenzonitril]
by: Dogan O.E.; Agar E.; Dege N.; Normaya E.; Sirat S.S.; Dzulkifli N.N.
Published: (2024)

Genoprotective potential of Macaranga species phytochemical compounds on HT-29 human colorectal adenocarcinoma cell line
by: Siew E.L.; Pearanpan L.; Zamkhuri Z.; Nordin F.J.; Ooi T.C.; Chan K.M.; Kamarozaman A.S.; Ahmat N.; Rajab N.F.
Published: (2023)

Synthesis, crystal structure, thermal analysis, Hirshfeld surface analysis and density functional theory study of Ru3(CO)9(µ-Ph2AsCH2AsPh2)(AsPh3)
by: Azharan H.I.M.N.; Sirat S.S.; Yusof E.N.M.; Rosli M.M.; Arshad S.; Pungot N.H.
Published: (2024)

New trisubstituted triruthenium carbonyl cluster containing mixed P/As ligands: synthesis, characterization, crystal structure, and Hirshfeld surface analysis of Ru3(CO)9(µ-Ph2P(CH2)4PPh2)(AsPh3)
by: Sirat S.S.; Arshad S.; Shawkataly O.B.
Published: (2024)

New trisubstituted triruthenium carbonyl cluster containing mixed P/As ligands: synthesis, characterization, crystal structure, and Hirshfeld surface analysis of Ru3(CO)9(μ-Ph2P(CH2)4PPh2)(AsPh3)
by: Sirat, et al.
Published: (2024)

Structural Characterization, DFT, Hirshfeld Surface Analysis and Antibacterial Activity of a Schiff Base Derived from Cyclohexanediamine
by: Nasaruddin N.H.; Ahmad S.N.; Sirat S.S.; Wai T.K.; Zakaria N.A.; Bahron H.
Published: (2021)

Tetradentate phenolic Schiff base ligands derived from aromatic diamine and their nickel (II) complexes: Synthesis, characterization, and in vitro anticancer screening
by: Ahmad S.N.; Bahron H.; Tajuddin A.M.; Ramasamy K.
Published: (2019)

Anticancer molecules from catharanthus roseus
by: Taher Z.M.; Agouillal F.; Lim J.R.; Marof A.Q.; Dailin D.J.; Nurjayadi M.; Razif E.N.M.; Gomaa S.E.; El Enshasy H.A.
Published: (2019)

OPTIMIZED SAMPLE PREPARATION TECHNIQUE FOR VISUALISATION OF THE ADHERENCE OF LACTOBACILLACEAE SP. TO HUMAN COLORECTAL ADENOCARCINOMA CELL LINE HT-29 BY FIELD EMISSION SCANNING ELECTRON MICROSCOPE
by: Ilyanie H.Y.; Muryany I.M.Y.; Huda-Faujan N.
Published: (2023)

Synthesis, characterization and anticancer activity of mono- and dinuclear Ni(II) and Co(II) complexes of a Schiff base derived from o-vanillin
by: Bahron H.; Khaidir S.S.; Tajuddin A.M.; Ramasamy K.; Yamin B.M.
Published: (2019)

Bis-pyrimidine acetamides: Design, synthesis and biological evaluation
by: Kumar S.; Lim S.M.; Ramasamy K.; Vasudevan M.; Shah S.A.A.; Narasimhan B.
Published: (2017)

Hydroxychavicol as a potential anticancer agent (Review)
by: Mohamad N.A.; Rahman A.A.; Kadir S.H.S.A.
Published: (2023)

Synthesis, in vitro thymidine phosphorylase inhibitory activity and molecular docking study of novel pyridine-derived bis-oxadiazole bearing bis-schiff base derivatives
by: Hussain R.; Rehman W.; Rahim F.; Khan S.; Alanazi A.S.; Alanazi M.M.; Rasheed L.; Khan Y.; Adnan. Ali. Shah S.; Taha M.
Published: (2023)

Microwave-assisted synthesis of triazole derivatives conjugated with piperidine as new anti-enzymatic agents
by: Virk N.A.; Rehman A.-U.; Abbasi M.A.; Siddiqui S.Z.; Iqbal J.; Rasool S.; Khan S.U.; Htar T.T.; Khalid H.; Laulloo S.J.; Ali Shah S.A.
Published: (2020)

Effectiveness of preventive medicine education and its determinants among medical students in Malaysia
by: Anil S.; Zawahir M.S.; Al-Naggar R.A.
Published: (2016)

Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
by: Rahim F.; Waseeq-Ur-Rehamn; Shehzad M.; Khan A.; Taha M.; Abid O.U.R.; Quereshi M.T.; Tauseef I.; Rehman W.
Published: (2016)

Crystal structure of 5,6,3′,4′,5′-pentamethoxy-flavone dihydrate, C20H24O9
by: Salihu A.S.; Salleh W.M.N.H.W.; Tajuddin A.M.; Ghani N.A.
Published: (2024)

Design, synthesis of triazole-based scaffolds, N-(substitutedphenyl)-2-(5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthiol)acetamides: As potential anti-cholinesterase agents for neurodegenerative diseases
by: Siddiqui S.Z.; Arfan M.; Abbasi M.A.; Aziz-ur-Rehman; Shah S.A.A.; Parveen R.; Ashraf M.; Solangi M.; Hussain S.; Khan K.M.
Published: (2023)

Synthesis, β-Glucuronidase Inhibition, and Molecular Docking Studies of 1,2,4-Triazole Hydrazones
by: Jamil W.; Kumari D.; Taha M.; Khan M.N.; Baharudin M.S.; Ali M.; Kanwal M.; Lashari M.S.; Khan K.M.
Published: (2018)

Synthesis and biological evaluation of heterocyclic 1,2,4-triazole scaffolds as promising pharmacological agents
by: Kumari M.; Tahlan S.; Narasimhan B.; Ramasamy K.; Lim S.M.; Shah S.A.A.; Mani V.; Kakkar S.
Published: (2021)

Quinolone Derivatives as Anticancer Agents: Importance in Medicinal Chemistry
by: Azzman N.; Anwar S.; Mohamed W.A.S.; Ahemad N.
Published: (2024)

Synthesis, anticancer, molecular docking and QSAR studies of benzoylhydrazone
by: Taha M.; Sultan S.; Herizal M.; Fatmi M.Q.; Selvaraj M.; Ramasamy K.; Halim S.A.; Lim S.M.; Rahim F.; Ashraf K.; Shehzad A.
Published: (2019)

Pattern of shisha and cigarette smoking in the general population in Malaysia
by: Al-Naggar R.A.; Bobryshev Y.V.; Anil S.
Published: (2014)

Rational design of bis-indolylmethane-oxadiazole hybrids as inhibitors of thymidine phosphorylase
by: Taha M.; Rashid U.; Imran S.; Ali M.
Published: (2018)