The Construction of CRISPR-Cas9 System Targeting Vector for CYP3A4 Gene in Hepatic Cell Lines

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The Construction of CRISPR-Cas9 System Targeting Vector for CYP3A4 Gene in Hepatic Cell Lines

Drug metabolism in the human liver initiated by Cytochrome P450 (CYP450) has been widely acknowledged. They oxidise drugs, harmful compounds, and endogenous molecules like steroids. In our research study, we mainly focused on CYP3A4 of the CYP450 subfamily that is widely available in the liver aroun...

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Bibliographic Details
Published in:	Journal of Advanced Research in Applied Sciences and Engineering Technology
Main Author:	Hatta F.H.M.; Aziz F.N.A.; Rehman S.-U.; Othman A.A.
Format:	Article
Language:	English
Published:	Semarak Ilmu Publishing 2025
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85192187841&doi=10.37934%2faraset.43.2.178188&partnerID=40&md5=c687df7c0639839dd4b59f88805137f3

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