Mutation analysis of BCR-ABL1 kinase domain in chronic myeloid leukemia patients with tyrosine kinase inhibitors resistance: a Malaysian cohort study

QR Code

Mutation analysis of BCR-ABL1 kinase domain in chronic myeloid leukemia patients with tyrosine kinase inhibitors resistance: a Malaysian cohort study

Objective: Mutational analysis of BCR::ABL1 kinase domain (KD) is a crucial component of clinical decision algorithms for chronic myeloid leukemia (CML) patients with failure or warning responses to tyrosine kinase inhibitor (TKI) therapy. This study aimed to detect BCR::ABL1 KD mutations in CML pat...

Full description

Bibliographic Details
Published in:	BMC Research Notes
Main Author:	Seman Z.A.; Ahid F.; Kamaluddin N.R.; Sahid E.N.M.; Esa E.; Said S.S.M.; Azman N.; Mat W.K.D.W.; Abdullah J.; Ali N.A.; Khalid M.K.N.M.; Yusoff Y.M.
Format:	Article
Language:	English
Published:	BioMed Central Ltd 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85191066262&doi=10.1186%2fs13104-024-06772-1&partnerID=40&md5=16f88fbdbffb24943a32696ab1a72323

Similar Items

Mutation analysis of BCR-ABL1 kinase domain in chronic myeloid leukemia patients with tyrosine kinase inhibitors resistance: a Malaysian cohort study
by: Abu Seman, et al.
Published: (2024)

Comprehensive analysis of mutations and clonal evolution patterns in a cohort of patients with cytogenetically normal acute myeloid leukemia
by: Mat Yusoff Y.; Ahid F.; Abu Seman Z.; Abdullah J.; Kamaluddin N.R.; Esa E.; Zakaria Z.
Published: (2021)

CNN-Based Classification of Acute Myeloid Leukemia Blood Samples
by: Ahmad A.R.; Zainudin N.A.; Radzi M.D.I.M.; Halim N.H.A.; Osman M.K.; Saad Z.
Published: (2024)

In vitro cytotoxicity effects of single and combination Nigella sativa and Zingiber zerumbet extracts on human myeloid leukemia (HL60) cells and its mode of cell death
by: Norfazlina M.N.; Farida Zuraina M.Y.; Rajab N.F.; Mohd Nazip S.; Rumiza A.R.; Suziana Zaila C.F.; Lek Mun L.; Nurshahirah N.; Florinsiah L.
Published: (2014)

Comparison of Clinicopathological Parameters, and Treatment Responses in Younger and Older Chronic Myeloid Leukaemia Patients Treated with Imatinib
by: Kamarudin A.F.; Palaniappan S.; Sabudin R.Z.A.R.; Shuib S.; Jamil S.A.M.; Tumian N.R.
Published: (2023)

Reducing Environmental Pollutants by using Triorganotin(IV)-Tyrosine Complexes that Prolong the Life of the Polymers used in Outdoor Patios
by: Arraq, et al.
Published: (2023)

Reducing Environmental Pollutants by using Triorganotin(IV)-Tyrosine Complexes that Prolong the Life of the Polymers used in Outdoor Patios
by: Arraq R.R.; Hadi A.G.; Ahmed D.S.; Zainulabdeen K.; Hashim H.; Ahmed A.A.; Yusop R.M.; Jawad A.H.; Mohammed S.A.; Al-Amiery A.; Yousif E.
Published: (2023)

Neuropsychological task outcomes among survivors of childhood acute lymphoblastic leukemia in Malaysia
by: Alias H.; Mohd Ranai N.; Lau S.C.D.; de Sonneville L.M.J.
Published: (2024)

Mutation Study of Malaysian Patients with Ornithine Transcarbamylase Deficiency: Clinical, Molecular, and Bioinformatics Analyses of Two Novel Missense Mutations of the OTC Gene
by: Ali E.Z.; Zakaria Y.; Mohd Radzi M.A.; Ngu L.H.; Jusoh S.A.
Published: (2018)

Computation of Neumann Localised Boundary Domain Integral Equations
by: Mohamed N.A.; Ibrahim N.F.; Mohamed N.F.; Norddin N.I.; Mohamed N.H.
Published: (2023)

Increased RUNX1 mutations in breast cancer disease progression
by: Ariffin N.S.
Published: (2024)

Mitochondrial DNA mutations in Malaysian female breast cancer patients
by: Omasanggar R.; Yu C.Y.; Ang G.Y.; Emran N.A.; Kitan N.; Baghawi A.; Ahmad A.F.; Abdullah M.A.; Teh L.K.; Maniam S.
Published: (2020)

Neuropsychological task outcomes among survivors of childhood acute lymphoblastic leukemia in Malaysia
by: Alias, et al.
Published: (2024)

Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma
by: Chow Y.P.; Tan L.P.; Chai S.J.; Abdul Aziz N.; Choo S.W.; Lim P.V.H.; Pathmanathan R.; Kornain N.K.M.; Lum C.L.; Pua K.C.; Yap Y.Y.; Tan T.Y.; Teo S.H.; Khoo A.S.-B.; Patel V.
Published: (2017)

Content-Based Image Retrieval in Medical Domain: A Review
by: Mohd Zin N.A.; Yusof R.; Lashari S.A.; Mustapha A.; Senan N.; Ibrahim R.
Published: (2018)

In vitro mutation of capsicum annuum L.Var. Kulai by gamma radiation
by: Abdullah S.; Shariffudin N.A.F.; Omar N.; Harun A.R.; Shamsudin S.
Published: (2019)

Affective Domain in Learning Taxonomy at Institution of Higher Education
by: Mahfuzah M.Z.; Fakhrurrazi M.Z.A.; Norhapizah M.B.
Published: (2022)

Domain expert maintainable inference knowledge of assessment task
by: Halim S.A.; Annamalai M.; Ahmad M.S.; Ahmad R.
Published: (2015)

Comparative Study on Different Color Spaces for Segmentation of Acute Leukemia using Automatic Otsu Clustering
by: Mohd Zairy S.M.; Hazwani Abd Halim N.; Sulaiman M.S.; Saad Z.
Published: (2022)

Increased RUNX1 mutations in breast cancer disease progression
by: Ariffin, et al.
Published: (2024)

Agent-based simulation in a normative environment using the EPMP domain
by: Hamid N.H.A.; Ahmad A.; Ahmad M.S.; Tang Y.C.A.; Mustapha A.
Published: (2013)

Helical integrity and microsolvation of transmembrane domains from Flaviviridae envelope glycoproteins
by: Jusoh S.A.; Helms V.
Published: (2011)

Hybrid PSO-CNN Model for Cross-Domain Adaptation Sentiment Analysis
by: Bahrin U.F.M.; Jantan H.
Published: (2024)

Integrated Clonal Accelerated Mutation Evolutionary Programming for Composite Compensation in Power System
by: Ismail S.A.; Musirin I.; Mansor M.H.; Hamid Z.A.; Jelani S.; Kumar A.V.S.
Published: (2024)

Determination of soil water content using time domain reflectometer (TDR) for clayey soil
by: Abdullah N.H.H.; Kuan N.W.; Ibrahim A.; Ismail B.N.; Majid M.R.A.; Ramli R.; Mansor N.S.
Published: (2018)

Self-Learning about Herbal and Dietary Supplements: Perspectives Using the Theoretical Domains Framework
by: Abd Wahab M.S.; Wan Ismail W.N.S.; Ali A.A.; Ibrahim N.; Othman N.; Mohd Nor Hazalin N.A.; Goh K.W.; Ming L.C.
Published: (2022)

Dynamic domain transformation resource scheduling approach: water irrigation scheduling for urban farming
by: Amerudin M.N.I.M.; Rahim S.K.N.A.; Omar N.; Sulaiman M.S.; Jaafar A.H.; Hamzah R.
Published: (2022)

Reverting TP53 Mutation in Breast Cancer Cells: Prime Editing Workflow and Technical Considerations
by: Abuhamad A.Y.; Mohamad Zamberi N.N.; Sheen L.; Naes S.M.; Mohd Yusuf S.N.H.; Ahmad Tajudin A.; Mohtar M.A.; Amir Hamzah A.S.; Syafruddin S.E.
Published: (2022)

Differential metabolomic pathway analysis in Malaysian childhood acute lymphoblastic leukemia patients treated with high-dose methotrexate
by: Razali R.H.; Teh L.K.; Salleh M.Z.; Teh K.H.; Mohd Ibrahim H.
Published: (2024)

High resolution time domain reflectometry and coaxial cable for soil nail monitoring
by: Ng W.K.; Ashaari Y.; Norshazrul M.Y.
Published: (2019)

Identifying and Validating Vocational Skills Domains and Indicators in Classroom Assessment Practices in TVET
by: M. Yusop S.R.; Rasul M.S.; Mohammad Yasin R.; Hashim H.U.
Published: (2023)

Discrete Mutative Particle Swarm Optimisation of MFCC computation for classifying hypothyroidal infant cry
by: Zabidi A.; Mansor W.; Khuan L.Y.; Yassin I.M.; Sahak R.
Published: (2010)

Identification of potential mutations associated with multidrug resistance among isolates of Mycobacterium tuberculosis in Malaysia by in silico screening
by: Teh H.W.; Citartan M.; Hamdani H.Y.; Salleh M.Z.; Teh L.K.; Noorizhab M.N.F.B.; Tang T.-H.
Published: (2023)

Nodamura virus B2 amino terminal domain sensitivity to small interfering RNA
by: Shaik Syed Ali P.; John J.; Selvaraj M.; Kek T.L.; Salleh M.Z.
Published: (2015)

Performance comparison between mutative and constriction PSO in optimizing MFCC for the classification of hypothyroid infant cry
by: Zabidi A.; Mansor W.; Lee Y.K.; Yassin I.M.; Sahak R.
Published: (2011)

Extension operators of circular intuitionistic fuzzy sets with triangular norms and conorms: Exploring a domain radius
by: Pratama D.; Yusoff B.; Abdullah L.; Kilicman A.; Kamis N.H.
Published: (2024)

Enhancement of the production of L-glutaminase, an anticancer enzyme, from Aeromonas veronii by adaptive and induced mutation techniques
by: Aravinth Vijay Jesuraj S.; Moklesur Rahman Sarker Md.; Ming L.C.; Marylin Jeya Praya S.; Ravikumar M.; Wui W.T.
Published: (2017)

A Systematic Review on Particle Swarm Optimization Towards Target Search in The Swarm Robotics Domain
by: Hamami M.G.M.; Ismail Z.H.
Published: (2022)

Diagnostic and therapeutic potential of shark variable new antigen receptor (VNAR) single domain antibody
by: Cheong W.S.; Leow C.Y.; Abdul Majeed A.B.; Leow C.H.
Published: (2020)

Exploring the Domains of Faculty Development Programmes for Malaysian Medical School Lecturers: A Qualitative Study
by: Nor M.Z.M.; Latif R.A.
Published: (2022)