| Summary: | Objective: The study explores the potential of Curcuma aeruginosa Roxb. extract for anti-inflammatory properties. Methods: Curcuma aeruginosa Roxb. simplicia was macerated with distilled ethanol. In vitro testing was done on Raw 264.7 macrophages to fulfill this aim by observing Tumor Necrosis Factor (TNF)-α, Interleukin (IL)-6 production and phagocytosis activity. The production of IL-6 and TNF-α were determined using the ELISA method while phagocytosis activity using the neutral red uptake method. Results: The results showed that Curcuma aeruginosa Roxb. extract inhibited production of TNF-α and IL-6 and phagocytic activity and on Raw 264.7 macrophages. Conclusion: The results demonstrated that Curcuma aeruginosa Roxb. extract could be developed as an anti-inflammatory, which can be improved as a novel pharmaceutical approach for treating inflammation-related illness. © 2024 The Authors. Published by Innovare Academic Sciences Pvt Ltd.
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