New benzimidazole based Schiff bases as potent anti-alzheimer agents: Synthesis, bio-evaluation and molecular docking study

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New benzimidazole based Schiff bases as potent anti-alzheimer agents: Synthesis, bio-evaluation and molecular docking study

In search of potent anti-Alzheimer agent benzimidazole based Schiff base derivatives (1–18) were synthesized and evaluated as dual inhibitor for acetylcholinesterase and butyrylcholinesterase enzymes. All analogs among the series except analog 1 and 16 showed a variable degree of inhibitory activity...

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Bibliographic Details
Published in:	Journal of Molecular Structure
Main Author:	Othman M.S.; Hayat S.; Rahim F.; Taha M.; Sajid M.; Khan S.; Iqbal W.; Shah S.A.A.; Fareid M.A.; Aboelnaga S.M.; Abdel-Hafez L.J.; Hafez M.M.
Format:	Article
Language:	English
Published:	Elsevier B.V. 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189482031&doi=10.1016%2fj.molstruc.2024.138058&partnerID=40&md5=f37b16662d6d00c6cee9b09b8d42da26

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