Exposure of Helicobacter pylori to clarithromycin in vitro resulting in the development of resistance and triggers metabolic reprogramming associated with virulence and pathogenicity

In H. pylori infection, antibiotic-resistance is one of the most common causes of treatment failure. Bacterial metabolic activities, such as energy production, bacterial growth, cell wall construction, and cell-cell communication, all play important roles in antimicrobial resistance mechanisms. Iden...

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Bibliographic Details
Published in:PLoS ONE
Main Author: Rosli N.A.; Al-Maleki A.R.; Loke M.F.; Tay S.T.; Rofiee M.S.; Teh L.K.; Salleh M.Z.; Vadivelu J.
Format: Article
Language:English
Published: Public Library of Science 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85186654327&doi=10.1371%2fjournal.pone.0298434&partnerID=40&md5=9c4ce3da287072d8f086e77cf3cf7d8e