Novel hydrazone schiff’s base derivatives of polyhydroquinoline: synthesis, in vitro prolyl oligopeptidase inhibitory activity and their Molecular docking study
This research work reports the synthesis of new derivatives of the hydrazone Schiff bases (1–17) based on polyhydroquinoline nucleus through multistep reactions. HR-ESIMS,1H- and 13C-NMR spectroscopy were used to structurally infer all of the synthesized compounds and lastly evaluated for prolyl oli...
Published in: | Journal of Biomolecular Structure and Dynamics |
---|---|
Main Author: | Talab F.; Alam A.; Zainab; Ullah S.; Elhenawy A.A.; Shah S.A.A.; Ali M.; Halim S.A.; Khan A.; Latif A.; Al-Harrasi A.; Ahmad M. |
Format: | Article |
Language: | English |
Published: |
Taylor and Francis Ltd.
2024
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85186418155&doi=10.1080%2f07391102.2024.2319677&partnerID=40&md5=3c25469e855ec58c109fbcd08ebaf2a6 |
Similar Items
-
Novel acyl hydrazide derivatives of polyhydroquinoline as potent anti-diabetic and anti-glycating agents: Synthesis, in vitro α-amylase, α-glucosidase inhibition and anti-glycating activity with molecular docking insights
by: Ur Rahman S.; Alam A.; Parveen Z.; Zainab; Assad M.; Adnan Ali Shah S.; Rafiq H.; Ayaz M.; Latif A.; Naveed Umar M.; Ali M.; Ahmad M.
Published: (2024) -
Synthesis and Molecular Docking Study of Hydrazone Schiff Bases of α-Naphthalene-Containing Alkyl Phenyl Ether Fragment as Potent α-Amylase and α-Glucosidase Inhibitors
by: Shah T.A.; Alam A.; Zainab; Assad M.; Parveen Z.; Rafiq H.; Ayaz M.; Shah S.A.A.; Latif A.; Ali M.; Ahmad M.
Published: (2024) -
Synthesis and Molecular Docking Study of Hydrazone Schiff Bases of α-Naphthalene-Containing Alkyl Phenyl Ether Fragment as Potent α-Amylase and α-Glucosidase Inhibitors
by: Shah, et al.
Published: (2024) -
Synthesis of Flurbiprofen Based Amide Derivatives as Potential Leads for Diabetic Management: In Vitro α-glucosidase Inhibition, Molecular Docking and DFT Simulation Approach
by: Alam A.; Zainab; Elhenawy A.A.; Ur Rehman N.; Shahidul Islam M.; Dahlous K.A.; Talab F.; Shah S.A.A.; Ali M.; Ahmad M.
Published: (2024) -
Synthesis, in vitro alpha-glucosidase inhibitory potential of benzimidazole bearing bis-Schiff bases and their molecular docking study
by: Rahim F.; Zaman K.; Taha M.; Ullah H.; Ghufran M.; Wadood A.; Rehman W.; Uddin N.; Shah S.A.A.; Sajid M.; Nawaz F.; Khan K.M.
Published: (2020)