Exploring the synthesis, molecular structure and biological activities of novel Bis-Schiff base derivatives: A combined theoretical and experimental approach

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Exploring the synthesis, molecular structure and biological activities of novel Bis-Schiff base derivatives: A combined theoretical and experimental approach

A library of six novel bis-Schiff base derivatives (2a-f) were synthesized, characterized through modern spectroscopic techniques and screened for their α-glucosidase and α-amylase inhibitory activities (in vitro). In the series, compound 2a (IC50 = 5.64 ± 2.22 µM) and 2f (IC50 = 22.78 ± 2.37 µM) we...

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Bibliographic Details
Published in:	Journal of Molecular Structure
Main Author:	Gul S.; Alam A.; Zainab; Assad M.; Elhenawy A.A.; Islam M.S.; Shah S.A.A.; Parveen Z.; Shah T.A.; Ahmad M.
Format:	Article
Language:	English
Published:	Elsevier B.V. 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85186267356&doi=10.1016%2fj.molstruc.2024.137828&partnerID=40&md5=4ca0f9b436b8e1627810d7db534f536a

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