| Summary: | Bladder stones can be classified as primary, secondary or migratory and the etiology can be multifactorial. Unlike kidney or ureter stones, bladder stones only constitute around 5% of all urinary tract stones. Generally, bladder stones occur in conditions such as bladder outlet obstruction, neurogenic bladder, chronic infection and presence of a foreign body. The prevalence is higher in males with a reported ratio of male to female of 4:1. Giant bladder stone is a rare condition, even more so, of a case of multiple huge stones. There are numerous case reports about a single giant bladder stone but not so in the case of multiple calculi. We report a case of a lady presented with a sudden onset of acute renal impairment with multiple huge bladder stones detected from imaging. Open cystolithotomy was done, and a few huge bladder stones were extracted. This case report is to illustrate a rare presentation of multiple giant bladder stones. © 2024, Faculty of Medicine, University of Malaya. All rights reserved.
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