A Review on the Potential of Application of CRISPR/Cas9 Technology in CYP3A4 and CYP2D6 Genes: A Way to Move Forward in Identifying New Drug Targets

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A Review on the Potential of Application of CRISPR/Cas9 Technology in CYP3A4 and CYP2D6 Genes: A Way to Move Forward in Identifying New Drug Targets

The cytochrome P450 (CYP) enzymes are of a ubiquitous heme-thiolate proteins family that plays an important role within the biotransformation of endogenous molecules and xenobiotics as today’s market is bio-transformed through CYP-mediated metabolism. Major CYP isoforms involved in most reactions ar...

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Bibliographic Details
Published in:	ASM Science Journal
Main Author:	Othman A.; Yusoff R.M.; Azam S.N.N.; Hassan A.Z.A.; Hatta F.H.
Format:	Article
Language:	English
Published:	Akademi Sains Malaysia 2022
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85185160496&doi=10.32802%2fasmscj.2022.999&partnerID=40&md5=589d5c94c24b720e79991449d6b02367

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