A Review on the Potential of Application of CRISPR/Cas9 Technology in CYP3A4 and CYP2D6 Genes: A Way to Move Forward in Identifying New Drug Targets
The cytochrome P450 (CYP) enzymes are of a ubiquitous heme-thiolate proteins family that plays an important role within the biotransformation of endogenous molecules and xenobiotics as today’s market is bio-transformed through CYP-mediated metabolism. Major CYP isoforms involved in most reactions ar...
| Published in: | ASM Science Journal |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Akademi Sains Malaysia
2022
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85185160496&doi=10.32802%2fasmscj.2022.999&partnerID=40&md5=589d5c94c24b720e79991449d6b02367 |