Synthesis of Indole Based Sulfonamide Derivatives as potent inhibitors of α-glucosidase and α-amylase in management of type-II diabetes

We have synthesized indole-based sulfonamides derivatives (1–10), characterized through NMR and HR-EIMS, and screened against α-glucosidase and α-amylase enzymes. All the synthesized analogues showed various degrees of inhibitory potential ranging between 1.10 ± 0.10 to 10.90 ± 0.20 µM (against α-gl...

Full description

Bibliographic Details
Published in:Chemical Data Collections
Main Author: Ullah W.; Rahim F.; Hayat S.; Ullah H.; Taha M.; Khan S.; Khaliq A.; Bibi S.; Gohar O.; Iqbal N.; Shah S.A.A.; Khan K.M.
Format: Data paper
Language:English
Published: Elsevier B.V. 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85185155619&doi=10.1016%2fj.cdc.2024.101122&partnerID=40&md5=387a1e0f2244a8a5519f954de0659ea7

Similar Items