Synthesis of Indole Based Sulfonamide Derivatives as potent inhibitors of α-glucosidase and α-amylase in management of type-II diabetes
We have synthesized indole-based sulfonamides derivatives (1–10), characterized through NMR and HR-EIMS, and screened against α-glucosidase and α-amylase enzymes. All the synthesized analogues showed various degrees of inhibitory potential ranging between 1.10 ± 0.10 to 10.90 ± 0.20 µM (against α-gl...
Published in: | Chemical Data Collections |
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Main Author: | |
Format: | Data paper |
Language: | English |
Published: |
Elsevier B.V.
2024
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85185155619&doi=10.1016%2fj.cdc.2024.101122&partnerID=40&md5=387a1e0f2244a8a5519f954de0659ea7 |