TRPM4 blocking antibody reduces neuronal excitotoxicity by specifically inhibiting glutamate-induced calcium influx under chronic hypoxia

QR Code

TRPM4 blocking antibody reduces neuronal excitotoxicity by specifically inhibiting glutamate-induced calcium influx under chronic hypoxia

Excitotoxicity arises from unusually excessive activation of excitatory amino acid receptors such as glutamate receptors. Following an energy crisis, excitotoxicity is a major cause for neuronal death in neurological disorders. Many glutamate antagonists have been examined for their efficacy in miti...

Full description

Bibliographic Details
Published in:	Neurobiology of Disease
Main Author:	Poore C.P.; Hazalin N.A.M.N.; Wei S.; Low S.W.; Chen B.; Nilius B.; Hassan Z.; Liao P.
Format:	Article
Language:	English
Published:	Academic Press Inc. 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182873860&doi=10.1016%2fj.nbd.2024.106408&partnerID=40&md5=7c1fb1b993feb06eb855d715bacc3bfe

Similar Items

TRPM4 blocking antibody reduces neuronal excitotoxicity by specifically inhibiting glutamate-induced calcium influx under chronic hypoxia
by: Poore, et al.
Published: (2024)

Effect of glutamic acid as additional monomer in biodegradable poly(xylitol sebacate glutamate) polymer
by: Sani N.F.M.; Jafri N.A.; Majid N.A.; Rosaidi N.A.; Onn M.
Published: (2021)

ANTIAPOPTOTIC EFFECT OF TAURINE AGAINST NMDA-INDUCED RETINAL EXCITOTOXICITY IN RATS
by: Lambuk L.; Iezhitsa I.; Agarwal R.; Bakar N.S.; Agarwal P.; Ismail N.M.
Published: (2019)

Production of polyclonal antibodies specific to river catfish Hemibagrus nemurus vitellogenin
by: Othman R.; Harmin S.A.; Mohtar S.H.; Sulong M.R.; Zan M.S.M.; Sulperi Z.M.
Published: (2023)

Hypoxia-Induced Neuroinflammation in Alzheimer’s Disease: Potential Neuroprotective Effects of Centella asiatica
by: Hambali A.; Kumar J.; Hashim N.F.M.; Maniam S.; Mehat M.Z.; Cheema M.S.; Mustapha M.; Adenan M.I.; Stanslas J.; Hamid H.A.
Published: (2021)

The study of monosodium glutamate application as a cross linker in tissue scaffold application
by: Nasir N.F.M.; Roslan M.R.; Cheng E.M.; Zulaini T.N.S.; Khalid M.F.A.; Mustafa W.A.; Noriman N.Z.; Dahham O.S.
Published: (2020)

Recognizing faces with normalized local Gabor features and Spiking Neuron Patterns
by: Kamaruzaman F.; Shafie A.A.
Published: (2016)

Mitragynine and its potential blocking effects on specific cardiac potassium channels
by: Tay Y.L.; Teah Y.F.; Chong Y.M.; Jamil M.F.A.; Kollert S.; Adenan M.I.; Wahab H.A.; Döring F.; Wischmeyer E.; Tan M.L.
Published: (2016)

India-Burma (Myanmar) Relations under British India Administration prior to 1937 Separation: Influx of the Indians and awakening of Nationalist Movements in Burma
by: Ayob, et al.
Published: (2024)

Modifications in Macular Perfusion and Neuronal Loss After Acute Traumatic Brain Injury
by: Hepschke J.L.; Laws E.; Bin Saliman N.H.; Juncu S.; Courtie E.; Belli A.; Blanch R.J.
Published: (2023)

Exposure to electrophiles impairs reactive persulfide-dependent redox signaling in neuronal cells
by: Ihara H.; Kasamatsu S.; Kitamura A.; Nishimura A.; Tsutsuki H.; Ida T.; Ishizaki K.; Toyama T.; Yoshida E.; Hamid H.A.; Jung M.; Matsunaga T.; Fujii S.; Sawa T.; Nishida M.; Kumagai Y.; Akaike T.
Published: (2017)

Thymoquinone prevents β-amyloid neurotoxicity in primary cultured cerebellar granule neurons
by: Ismail N.; Ismail M.; Mazlan M.; Latiff L.A.; Imam M.U.; Iqbal S.; Azmi N.H.; Ghafar S.A.A.; Chan K.W.
Published: (2013)

Biopurification of monoclonal antibody (mAb) through crystallisation
by: Chen W.; Li X.; Guo M.; Link F.J.; Ramli S.S.; Ouyang J.; Rosbottom I.; Heng J.Y.Y.
Published: (2021)

Effect of Temperature on Calcium Carbonate Precipitation in Biomimetic Calcium Chloride Solution
by: Fatheen I.N.M.R.; Syuhani C.H.; Fazlena H.; Miradatul N.M.R.; Harumi V.
Published: (2021)

Seropositivity and serointensity of Toxoplasma gondii antibodies and DNA among patients with schizophrenia
by: Omar A.; Bakar O.C.; Adam N.F.; Osman H.; Osman A.; Suleiman A.H.; Manaf M.R.A.; Selamat M.I.
Published: (2015)

Virgin Coconut Oil-Induced Neuroprotection in Lipopolysaccharide-Challenged Rats is Mediated, in Part, Through Cholinergic, Anti-Oxidative and Anti-Inflammatory Pathways
by: Rahim N.S.; Lim S.M.; Mani V.; Hazalin N.A.M.N.; Majeed A.B.A.; Ramasamy K.
Published: (2021)

Current progress of immunoinformatics approach harnessed for cellular- and antibody-dependent vaccine design
by: Kazi A.; Chuah C.; Majeed A.B.A.; Leow C.Y.; Lim B.H.
Published: (2018)

Cytotoxic and antibacterial activities of endophytic fungi isolated from plants at the National Park, Pahang, Malaysia
by: Hazalin N.A.M.N.; Ramasamy K.; Lim S.M.; Wahab I.A.; Cole A.L.J.; Abdul Majeed A.B.
Published: (2009)

Sinterability of Calcium Phosphate through Rapid Sintering
by: Natasha A.N.; Ramesh S.; Tan C.Y.; Bang L.T.
Published: (2021)

Production of monoclonal antibodies against Legionella pneumophila serogroup 1 for development of in-house immunodiagnostic assay
by: Yahaya N.; Kaspan S.; Pit S.; Abdullah N.R.
Published: (2006)

Diagnostic and therapeutic potential of shark variable new antigen receptor (VNAR) single domain antibody
by: Cheong W.S.; Leow C.Y.; Abdul Majeed A.B.; Leow C.H.
Published: (2020)

Dual function of unified adaptive linear neurons based fundamental component extraction algorithm for shunt active power filter operation
by: Rahman N.F.A.; Radzi M.A.M.; Soh A.C.; Mariun N.; Rahim N.A.
Published: (2015)

Protective effect of Phaleria macrocarpa Methanolic Fruit Extract against Oxidative Stress in Brine Shrimps
by: Hazalin N.A.M.N.; Halim H.; Rosli I.F.; Nazri N.A.; Mohsin H.F.; Zohdi R.M.; Ariestanti D.M.; James R.J.
Published: (2024)

Immunophenotyping of Gastritis, Gastric Ulcer and Gastric Cancer using a Cluster of Differentiation (CD) Antibody Microarray
by: Hanafiah A.; Sukri A.; Kosai N.R.; Shuhaili M.A.; Taher M.M.; Ali R.A.R.
Published: (2023)

Prevalence and risk factors of hepatitis C virus infection in haemodialysis patients: Testing antibodies, RNA and genotypes
by: Al-Kubaisy W.; Noor N.A.M.; Ibrahim N.S.N.; Al-Nasirie U.
Published: (2015)

Block Chain Technology Application to the Banking Sector
by: Alwi S.; Malan I.N.B.; Yusof S.H.; Mustafa M.
Published: (2023)

Densification of Calcium Phosphate from Biogenic Waste for Biomedical Application
by: Nawawi N.A.; Azmi F.A.; Azizan A.; Bang L.T.
Published: (2023)

Effect of sintering temperature on zinc substituted calcium phosphate ceramics
by: Mardziah C.M.; Abdul Wahid M.F.; Hyie K.M.; Masdek N.R.N.; Salleh Z.
Published: (2017)

Progress of Kinetic Inductance Detectors on Calcium Fluoride for Astroparticle physics
by: Mohamad Z.; Ishidoshiro K.; Kishimoto Y.; Mima S.; Taino T.; Hosokawa K.; Nakamura K.; Eizuka M.; Ito R.; Kawamura H.
Published: (2022)

Kinetic inductance detectors on calcium fluoride substrate for astroparticle physics
by: Ishidoshiro K.; Kobayashi T.; Hosokawa K.; Kawamura Y.; Kamei Y.; Mima S.; Otani C.; Suzuki A.A.; Zulfakri M.; Taino T.
Published: (2023)

Bearing strength of concrete for difference heights of concrete blocks
by: Md Zain M.R.; Yahya N.A.; Dhanasekar M.; Zain M.; Oh C.L.; Lee S.W.
Published: (2018)

The One with Many Facets: Anti-Glycine Receptor Antibodies-Related Parkinsonism with Complex Visual Phenomena and Stiff-Limb Syndrome
by: Mohd Fauzi N.A.; Mohd Nazi N.N.; Wan Mohd Azam E.R.; P. Bhatia K.
Published: (2024)

Mechanical properties of biaxial interlocking block (BIB) walling system
by: Aziz F.; Arshad M.F.; Mansor H.; Maizir H.; Suryanita R.; Salehuddin N.A.
Published: (2023)

A Comparison of the Motifs on Kuala Terengganu Block Batik Sarong
by: Legino, et al.
Published: (2023)

Analysis of expression of vitamin E-binding proteins in H2O2induced SK-N-SH neuronal cells supplemented with α-tocopherol and tocotrienol-rich fraction
by: Chiroma A.A.; Khaza'ai H.; Hamid R.A.; Chang S.K.; Zakaria Z.A.; Zainal Z.
Published: (2020)

Supramolecular Nested Microbeads as Building Blocks for Macroscopic Self-Healing Scaffolds
by: Yu Z.; Liu J.; Tan C.S.Y.; Scherman O.A.; Abell C.
Published: (2018)

Preparation of Agarose-based Biopolymer Electrolytes Containing Calcium Thiocyanate: Electrical and Electrochemical Properties
by: Rafi N.S.M.; Abidin S.Z.Z.; Majid S.R.; Zakaria R.
Published: (2022)

Effect of several calcination temperature on different concentration zinc substituted calcium phosphate ceramics
by: Wahid M.F.A.; Hyie K.M.; Mardziah C.M.; Nik Roselina N.R.
Published: (2015)

Unlocking the Microbial Potential of Intercalated Calcium-aluminum Layered Double Hydroxide-palmitic Acid
by: Johari N.A.; Ghazali S.A.I.S.M.; Ismail N.H.; Ariffin S.; Poddar S.; Biswas H.S.
Published: (2024)

Antisperm Antibody Testing: A Comprehensive Review of Its Role in the Management of Immunological Male Infertility and Results of a Global Survey of Clinical Practices
by: Gupta S.; Sharma R.; Agarwal A.; Boitrelle F.; Finelli R.; Farkouh A.; Saleh R.; Abdel-Meguid T.A.-A.; Gül M.; Zilaitiene B.; Ko E.; Rambhatla A.; Zini A.; Leisegang K.; Kuroda S.; Henkel R.; Cannarella R.; Palani A.; Cho C.-L.; Ho C.C.K.; Zylbersztejn D.S.; Pescatori E.; Chung E.; Dimitriadis F.; Pinggera G.-M.; Busetto G.M.; Balercia G.; Salvio G.; Colpi G.M.; Çeker G.; Taniguchi H.; Kandil H.; Park H.J.; Rosas I.M.; de la Rosette J.; Cardoso J.P.G.; Ramsay J.; Alvarez J.; Molina J.M.C.; Khalafalla K.; Bowa K.; Tremellen K.; Evgeni E.; Rocco L.; Peña M.G.R.; Sabbaghian M.; Martinez M.; Arafa M.; Al-Marhoon M.S.; Tadros N.; Garrido N.; Rajmil O.; Sengupta P.; Vogiatzi P.; Kavoussi P.; Birowo P.; Kosgi R.; Bani-Hani S.; Micic S.; Parekattil S.; Jindal S.; Le T.V.; Mostafa T.; Toprak T.; Morimoto Y.; Malhotra V.; Aghamajidi A.; Durairajanayagam D.; Shah R.
Published: (2022)