New piperidinyl heterocyclic azoles acquired through Li(I)-catalyzed reactions: Anti-enzymatic, ADME and computational studies

A biological impact of the fused heterocyclic rings as anti-enzymatic agents was explored through experimental, theoretical and computational studies. The targeted hybrids of 1,2,4-triazole (8a–q) were synthesized through multistep protocol. Initially, the carboxylate 3 was synthesized through stirr...

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Bibliographic Details
Published in:Journal of Molecular Structure
Main Author: Hamid S.; Amjad H.; Abbasi M.A.; Siddiqui S.Z.; Ashraf M.; Iqbal J.; Farhan M.; Rasool S.; Shah S.A.A.; Imran S.; Rehman M.T.; Rehman A.-U.
Format: Article
Language:English
Published: Elsevier B.V. 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182735120&doi=10.1016%2fj.molstruc.2024.137493&partnerID=40&md5=e0b65c9ed3a624a2476b227d81a22789