The role of commonly used transition metals in total synthesis of indole alkaloids

This Paper reviews the most recent advances in synthesizing indole alkaloids using transition metal-catalyzed methods. The essential class of natural substances known as indole alkaloids has several biological effects, including anti-inflammatory, anti-cancer, and anti-bacterial properties. Although...

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Published in:Arabian Journal of Chemistry
Main Author: Hannan Khan A.; Altaf S.; Rasool N.; Mubarik A.; Ahmad M.; Shah S.A.A.; Imran S.; Bajaber M.A.
Format: Review
Language:English
Published: Elsevier B.V. 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180548183&doi=10.1016%2fj.arabjc.2023.105523&partnerID=40&md5=e891429bf231a5144d5b222035bb5c0a
id 2-s2.0-85180548183
spelling 2-s2.0-85180548183
Hannan Khan A.; Altaf S.; Rasool N.; Mubarik A.; Ahmad M.; Shah S.A.A.; Imran S.; Bajaber M.A.
The role of commonly used transition metals in total synthesis of indole alkaloids
2024
Arabian Journal of Chemistry
17
2
10.1016/j.arabjc.2023.105523
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180548183&doi=10.1016%2fj.arabjc.2023.105523&partnerID=40&md5=e891429bf231a5144d5b222035bb5c0a
This Paper reviews the most recent advances in synthesizing indole alkaloids using transition metal-catalyzed methods. The essential class of natural substances known as indole alkaloids has several biological effects, including anti-inflammatory, anti-cancer, and anti-bacterial properties. Although there are numerous known natural sources of indole alkaloids, due to their scarcity and complexity, total synthesis has emerged as a promising technique of manufacture. Transition metal-catalyzed methods have become efficient tools for synthesizing indole alkaloids due to their high selectivity and efficiency. The various metal-catalyzed reactions that are used to synthesize indole alkaloids are discussed in this paper, including cross-coupling, cycloaddition, and oxidative cyclization reactions in last five years. © 2023 The Authors
Elsevier B.V.
18785352
English
Review
All Open Access; Gold Open Access
author Hannan Khan A.; Altaf S.; Rasool N.; Mubarik A.; Ahmad M.; Shah S.A.A.; Imran S.; Bajaber M.A.
spellingShingle Hannan Khan A.; Altaf S.; Rasool N.; Mubarik A.; Ahmad M.; Shah S.A.A.; Imran S.; Bajaber M.A.
The role of commonly used transition metals in total synthesis of indole alkaloids
author_facet Hannan Khan A.; Altaf S.; Rasool N.; Mubarik A.; Ahmad M.; Shah S.A.A.; Imran S.; Bajaber M.A.
author_sort Hannan Khan A.; Altaf S.; Rasool N.; Mubarik A.; Ahmad M.; Shah S.A.A.; Imran S.; Bajaber M.A.
title The role of commonly used transition metals in total synthesis of indole alkaloids
title_short The role of commonly used transition metals in total synthesis of indole alkaloids
title_full The role of commonly used transition metals in total synthesis of indole alkaloids
title_fullStr The role of commonly used transition metals in total synthesis of indole alkaloids
title_full_unstemmed The role of commonly used transition metals in total synthesis of indole alkaloids
title_sort The role of commonly used transition metals in total synthesis of indole alkaloids
publishDate 2024
container_title Arabian Journal of Chemistry
container_volume 17
container_issue 2
doi_str_mv 10.1016/j.arabjc.2023.105523
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180548183&doi=10.1016%2fj.arabjc.2023.105523&partnerID=40&md5=e891429bf231a5144d5b222035bb5c0a
description This Paper reviews the most recent advances in synthesizing indole alkaloids using transition metal-catalyzed methods. The essential class of natural substances known as indole alkaloids has several biological effects, including anti-inflammatory, anti-cancer, and anti-bacterial properties. Although there are numerous known natural sources of indole alkaloids, due to their scarcity and complexity, total synthesis has emerged as a promising technique of manufacture. Transition metal-catalyzed methods have become efficient tools for synthesizing indole alkaloids due to their high selectivity and efficiency. The various metal-catalyzed reactions that are used to synthesize indole alkaloids are discussed in this paper, including cross-coupling, cycloaddition, and oxidative cyclization reactions in last five years. © 2023 The Authors
publisher Elsevier B.V.
issn 18785352
language English
format Review
accesstype All Open Access; Gold Open Access
record_format scopus
collection Scopus
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