The role of commonly used transition metals in total synthesis of indole alkaloids

This Paper reviews the most recent advances in synthesizing indole alkaloids using transition metal-catalyzed methods. The essential class of natural substances known as indole alkaloids has several biological effects, including anti-inflammatory, anti-cancer, and anti-bacterial properties. Although...

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书目详细资料
发表在:Arabian Journal of Chemistry
主要作者: Hannan Khan A.; Altaf S.; Rasool N.; Mubarik A.; Ahmad M.; Shah S.A.A.; Imran S.; Bajaber M.A.
格式: Review
语言:English
出版: Elsevier B.V. 2024
在线阅读:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180548183&doi=10.1016%2fj.arabjc.2023.105523&partnerID=40&md5=e891429bf231a5144d5b222035bb5c0a
实物特征
总结:This Paper reviews the most recent advances in synthesizing indole alkaloids using transition metal-catalyzed methods. The essential class of natural substances known as indole alkaloids has several biological effects, including anti-inflammatory, anti-cancer, and anti-bacterial properties. Although there are numerous known natural sources of indole alkaloids, due to their scarcity and complexity, total synthesis has emerged as a promising technique of manufacture. Transition metal-catalyzed methods have become efficient tools for synthesizing indole alkaloids due to their high selectivity and efficiency. The various metal-catalyzed reactions that are used to synthesize indole alkaloids are discussed in this paper, including cross-coupling, cycloaddition, and oxidative cyclization reactions in last five years. © 2023 The Authors
ISSN:18785352
DOI:10.1016/j.arabjc.2023.105523